Kjær, Michael. Role of Extracellular Matrix in Adaptation of Tendon and Skeletal Muscle to
Mechanical Loading. Physiol Rev 84: 649–698, 2004; 10.1152/physrev. 00031.2003.—The …

Titin is a filamentous protein spanning the half-sarcomere, with spring-like properties in the I-
band region. Various structural, signaling, and mechanical functions have been associated …

Muscle-driven simulations of human and animal motion are widely used to complement
physical experiments for studying movement dynamics. Musculotendon models are an …

Recent studies have demonstrated a role for the elastic protein titin in active muscle, but the
mechanisms by which titin plays this role remain to be elucidated. In active muscle, Ca2+ …

Titin (also known as connectin) is a giant protein with a wide range of cellular functions,
including providing muscle cells with elasticity. Its physiological extension is largely derived …

In contrast to isometric and shortening contractions, many observations made on actively
lengthening muscles cannot be readily explained with the sliding filament and cross-bridge …

When active muscles are stretched, our understanding of muscle function is stretched as
well. Our understanding of the molecular mechanisms of concentric contraction has …

For the past 60 years, muscle contraction had been thought to be governed exclusively by
the contractile filaments, actin, and myosin. This thinking explained most observations for …

Muscle contraction and force regulation in skeletal muscle have been thought to occur
exclusively through the relative sliding of and the interaction between the contractile …

Eccentric muscle properties are not well characterized by the current paradigm of the
molecular mechanism of contraction: the cross-bridge theory. Findings of force contributions …