Rationale The chronic mild stress (CMS) paradigm was first described almost 40 years ago
and has become a widely used model in the search for antidepressant drugs for major …

Understanding how neuronal activity patterns in the brain correlate with complex behavior is
one of the primary goals of modern neuroscience. Chemical transmission is the major way of …

Various exercise-training types are known to prevent depression, but mechanisms
underlying their beneficial effects remain unknown. In the present study, the preconditioning …

The research was oriented towards the preparation of aerogel particles based on egg white
and whey protein isolate using various dispersion methods: dripping, spraying, and …

The nasal drug delivery route has distinct advantages, such as high bioavailability, a rapid
therapeutic effect, non-invasiveness, and ease of administration. This article presents the …

Fetal development is susceptible to environmental factors. One such factor is exposure to
stress during pregnancy. The present study aimed to investigate the effects of chronic …

We have previously described the LCGA-17 peptide as a novel anxiolytic and
antidepressant candidate that acts through the α2δ VGCC (voltage-gated calcium channel) …

Describing certain animal behaviours as 'depression-like'or 'depressive'has become
common across several fields of research. These typically involve unusually low activity or …

Objectives In the study, we examined the effects of ketamine and extremely low‐frequency
electromagnetic fields (ELF‐EMF) on depression‐like behavior, learning and memory …

The inducible nitric oxide synthase/nitric oxide (iNOS/NO) signaling pathway and
inflammatory cytokines play important roles in the pathogenesis of exercise-induced fatigue …