Mass spectrometry approaches to glycomic and glycoproteomic analyses
Glycomic and glycoproteomic analyses involve the characterization of oligosaccharides
(glycans) conjugated to proteins. Glycans are produced through a complicated nontemplate …
(glycans) conjugated to proteins. Glycans are produced through a complicated nontemplate …
Protein analysis by shotgun/bottom-up proteomics
According to Genome Sequencing Project statistics (http://www. ncbi. nlm. nih.
gov/genomes/static/gpstat. html), as of February 16, 2012, complete gene sequences have …
gov/genomes/static/gpstat. html), as of February 16, 2012, complete gene sequences have …
Oligosaccharide analysis by mass spectrometry: a review of recent developments
Carbohydrates are central players in a number of important biological processes including
cell signaling, cell adhesion, and the regulation of biochemical pathways. Unlike nucleic …
cell signaling, cell adhesion, and the regulation of biochemical pathways. Unlike nucleic …
High-sensitivity analytical approaches for the structural characterization of glycoproteins
1.1. General Considerations Structural intricacies of carbohydrate molecules and their
propensity to form varied linkages, substitutions, and branching patterns have fascinated …
propensity to form varied linkages, substitutions, and branching patterns have fascinated …
Annotation and structural elucidation of bovine milk oligosaccharides and determination of novel fucosylated structures
DL Aldredge, MR Geronimo, S Hua, CC Nwosu… - …, 2013 - academic.oup.com
Bovine milk oligosaccharides (BMOs) are recognized by the dairy and food industries, as
well as by infant formula manufacturers, as novel, high-potential bioactive food ingredients …
well as by infant formula manufacturers, as novel, high-potential bioactive food ingredients …
High resolution mass spectrometry based techniques at the crossroads of metabolic pathways
C Junot, F Fenaille, B Colsch… - Mass spectrometry …, 2014 - Wiley Online Library
The metabolome is the set of small molecular mass compounds found in biological media,
and metabolomics, which refers to as the analysis of metabolome in a given biological …
and metabolomics, which refers to as the analysis of metabolome in a given biological …
Comprehensive structural glycomic characterization of the glycocalyxes of cells and tissues
The glycocalyx comprises glycosylated proteins and lipids and fcorms the outermost layer of
cells. It is involved in fundamental inter-and intracellular processes, including non-self-cell …
cells. It is involved in fundamental inter-and intracellular processes, including non-self-cell …
Building a PGC-LC-MS N-glycan retention library and elution mapping resource
JL Abrahams, MP Campbell, NH Packer - Glycoconjugate journal, 2018 - Springer
Porous graphitised carbon-liquid chromatography (PGC-LC) has been proven to be a
powerful technique for the analysis and characterisation of complex mixtures of isomeric and …
powerful technique for the analysis and characterisation of complex mixtures of isomeric and …
Glycosylation characteristics of colorectal cancer
S Holst, M Wuhrer, Y Rombouts - Advances in cancer research, 2015 - Elsevier
Glycans on proteins and lipids are known to alter with malignant transformation. The study of
these may contribute to the discovery of biomarkers and treatment targets as well as …
these may contribute to the discovery of biomarkers and treatment targets as well as …
GPQuest: a spectral library matching algorithm for site-specific assignment of tandem mass spectra to intact N-glycopeptides
Glycoprotein changes occur in not only protein abundance but also the occupancy of each
glycosylation site by different glycoforms during biological or pathological processes. Recent …
glycosylation site by different glycoforms during biological or pathological processes. Recent …