Oral nanomedicine: challenges and opportunities
Compared to injection administration, oral administration is free of discomfort, wound
infection, and complications and has a higher compliance rate for patients with diverse …
infection, and complications and has a higher compliance rate for patients with diverse …
Short-chain fatty acids: linking diet, the microbiome and immunity
The short-chain fatty acids (SCFAs) butyrate, propionate and acetate are microbial
metabolites and their availability in the gut and other organs is determined by environmental …
metabolites and their availability in the gut and other organs is determined by environmental …
Adoptive Treg therapy with metabolic intervention via perforated microneedles ameliorates psoriasis syndrome
W Zhang, Y Chen, Z Zhao, H Zheng, S Wang, Z Liao… - Science …, 2023 - science.org
Regulatory T (Treg) cells underlie multiple autoimmune disorders and potentialize an anti-
inflammation treatment with adoptive cell therapy. However, systemic delivery of cellular …
inflammation treatment with adoptive cell therapy. However, systemic delivery of cellular …
[HTML][HTML] Gut microbial metabolite butyrate and its therapeutic role in inflammatory bowel disease: a literature review
Background and objective: Inflammatory bowel disease (IBD), including Crohn's disease
and ulcerative colitis, is a chronic inflammatory disorder characterized by aberrant immune …
and ulcerative colitis, is a chronic inflammatory disorder characterized by aberrant immune …
Delivery of short chain fatty acid butyrate to overcome Fusobacterium nucleatum-induced chemoresistance
L Chen, R Zhao, Z Kang, Z Cao, N Liu, J Shen… - Journal of Controlled …, 2023 - Elsevier
The gut microbiota is closely associated with the progression of colorectal cancer (CRC) in
which Fusobacterium nucleatum (F. nucleatum) was found to induce cancer resistance to …
which Fusobacterium nucleatum (F. nucleatum) was found to induce cancer resistance to …
An Engineered Butyrate-Derived Polymer Nanoplatform as a Mucosa-Healing Enhancer Potentiates the Therapeutic Effect of Magnolol in Inflammatory Bowel Disease
X Fan, Z Zhang, W Gao, Q Pan, K Luo, B He, Y Pu - ACS nano, 2023 - ACS Publications
Colonic epithelial damage and dysregulated immune response are crucial factors in the
progression and exacerbation of inflammatory bowel disease (IBD). Nanoenabled targeted …
progression and exacerbation of inflammatory bowel disease (IBD). Nanoenabled targeted …
[PDF][PDF] Commensal bacteria signal through TLR5 and AhR to improve barrier integrity and prevent allergic responses to food
AM Kemter, RT Patry, J Arnold, LA Hesser, E Campbell… - Cell reports, 2023 - cell.com
The increasing prevalence of food allergies has been linked to reduced commensal
microbial diversity. In this article, we describe two features of allergy-protective Clostridia …
microbial diversity. In this article, we describe two features of allergy-protective Clostridia …
[PDF][PDF] Glycosylation-modified antigens as a tolerance-inducing vaccine platform prevent anaphylaxis in a pre-clinical model of food allergy
The only FDA-approved oral immunotherapy for a food allergy provides protection against
accidental exposure to peanuts. However, this therapy often causes discomfort or side …
accidental exposure to peanuts. However, this therapy often causes discomfort or side …
Contributions of the early-life microbiome to childhood atopy and asthma development
H Steininger, J Moltzau-Anderson, SV Lynch - Seminars in Immunology, 2023 - Elsevier
The rapid rise in atopy and asthma in industrialized nations has led to the identification of
early life environmental factors that promote these conditions and spurred research into how …
early life environmental factors that promote these conditions and spurred research into how …
In vitro assessment of the effect of four polysaccharides on intestinal bacteria of mice with colitis
S Zhang, Y Sun, Q Nie, J Hu, W Su, Z Guo… - Food …, 2023 - Wiley Online Library
Polysaccharides are typically resistant to digestion in the gastrointestinal tract and are
instead degraded by gut microbiota in the colon. As such, they are commonly employed as …
instead degraded by gut microbiota in the colon. As such, they are commonly employed as …