Physical activity decreases the risk of a network of diseases, and exercise may be
prescribed as medicine for lifestyle-related disorders such as type 2 diabetes, dementia …

The health benefits of exercise are well-recognized and are observed across multiple organ
systems. These beneficial effects enhance overall resilience, healthspan and longevity. The …

The human ageing process is universal, ubiquitous and inevitable. Every physiological
function is being continuously diminished. There is a range between two distinct phenotypes …

Background Anxiety and depression symptoms in pregnancy typically affect between 10 and
25% of pregnant individuals. Elevated symptoms of depression and anxiety are associated …

Aging induces molecular, cellular and functional changes in the adult brain that drive
cognitive decline and increase vulnerability to dementia-related neurodegenerative …

With the explosion of neuroimaging, differences between male and female brains have been
exhaustively analyzed. Here we synthesize three decades of human MRI and postmortem …

Physical activity can treat and prevent depressive symptoms, but its antidepressant
mechanisms are yet to be established. In this review, we comprehensively assess key …

Reversing brain aging may be possible through systemic interventions such as exercise. We
found that administration of circulating blood factors in plasma from exercised aged mice …

Women are at twice the risk for anxiety and depression disorders as men are, although the
underlying biological factors and mechanisms are largely unknown. In this review, we …

Positive effects from sports are achieved primarily through physical activity, but secondary
effects bring health benefits such as psychosocial and personal development and less …