In recent years, the mathematical and computational sciences have developed novel
methodologies and insights that can aid in designing advanced bioreactors, microfluidic …

Ubiquitous in embryonic development, tissue fusion is of interest to tissue engineers who
use tissue spheroids or organoids as building blocks of three-dimensional (3D) multicellular …

Since its beginnings, three-dimensional printing (3DP) technology has been successful
because of ongoing advances in operating principles, the range of materials and cost …

The formation of spherical aggregates during the growth of cell population has long been
observed under various conditions. We observed the formation of such aggregates during …

In vitro tumor models consisting of cell spheroids are increasingly used for mechanistic
studies and pharmacological testing. However, unless vascularized, the availability of …

Tissue engineering has enabled the creation of strategies and solutions in the biomedical
area, which have widely benefited patients suffering from different conditions. In recent …

Naturally derived hydrogels are the most common bioink material for droplet-based
bioprinting. The mechanical stability of the printed construct and the cell viability are closely …

A long‐standing problem in tissue engineering is the biofabrication of perfusable tissue
constructs that can be readily connected to the patient's vasculature. It was partially solved …

By delivering cells and extracellular matrix one layer at a time, 3D bioprinting enables the
fabrication of multicellular structures of precise shape and architecture akin to native tissues …

Tissue engineers seek to build living tissue constructs for replacing or repairing damaged
tissues. Computational methods foster tissue engineering by pointing out dominant …