Objective Impairing emotional outbursts, defined by extreme anger or distress in response to
relatively ordinary frustrations and disappointments, impact all mental health care systems …

Objective Childhood irritability, operationalized as disproportionate and frequent temper
tantrums and low frustration tolerance relative to peers, is a transdiagnostic symptom across …

Irritability cuts across many pediatric disorders and is a common presenting complaint in
child psychiatry; however, its neural mechanisms remain unclear. One core …

Pediatric irritability is the most robust indicator of transdiagnostic psychopathology risk. It is
associated with altered neural reward processing, including neural networks related to …

Objective Irritability is a common characteristic in ADHD. We examined whether dysfunction
in neural connections supporting threat and reward processing was related to irritability in …

Objective The need to understand and treat childhood chronic irritability (CI; ie frequent
temper loss and angry/irritable mood) is imperative. CI predicts impairment across …

Background Mood disturbances have historically remained a core criterion in diagnosing
major depressive episode. DSMs have illustrated this criterion with depressed, hopeless …

Background Attention deficit hyperactivity disorder (ADHD) and irritability commonly co‐
occur, and follow similar developmental trajectories from childhood to adolescence …

Irritability, or an increased proneness to frustration and anger, is common in youth; however,
few studies have examined neurostructural correlates of irritability in children. The purpose …

Externalizing psychopathology in childhood is a predictor of poor outcomes across the
lifespan. Children exhibiting elevated externalizing symptoms also commonly show emotion …