Bioresponsive drug delivery systems for the treatment of inflammatory diseases

Y Dou, C Li, L Li, J Guo, J Zhang - Journal of Controlled Release, 2020 - Elsevier
Inflammation is intimately related to the pathogenesis of numerous acute and chronic
diseases like cardiovascular disease, inflammatory bowel disease, rheumatoid arthritis, and …

Near-infrared fluorescence imaging in immunotherapy

Y Ji, C Jones, Y Baek, GK Park, S Kashiwagi… - Advanced drug delivery …, 2020 - Elsevier
Near-infrared (NIR) light possesses many suitable optophysical properties for medical
imaging including low autofluorescence, deep tissue penetration, and minimal light …

Mechanical strength, biodegradation, and in vitro and in vivo biocompatibility of Zn biomaterials

D Zhu, I Cockerill, Y Su, Z Zhang, J Fu… - … applied materials & …, 2019 - ACS Publications
Zn-based biomaterials have emerged as promising new types of bioresorbable metallics
applicable to orthopedic devices, cardiovascular stents, and other medical applications …

Non-proinflammatory and responsive nanoplatforms for targeted treatment of atherosclerosis

Y Dou, Y Chen, X Zhang, X Xu, Y Chen, J Guo… - Biomaterials, 2017 - Elsevier
Atherosclerosis is the leading cause of many fatal cardiovascular and cerebrovascular
diseases. Whereas nanomedicines are promising for targeted therapy of atherosclerosis …

Current development of nano-drug delivery to target macrophages

D Cai, W Gao, Z Li, Y Zhang, L Xiao, Y Xiao - Biomedicines, 2022 - mdpi.com
Macrophages are the most important innate immune cells that participate in various
inflammation-related diseases. Therefore, macrophage-related pathological processes are …

Imaging in chronic wound diagnostics

S Li, AH Mohamedi, J Senkowsky, A Nair… - Advances in wound …, 2020 - liebertpub.com
Significance: Chronic wounds affect millions of patients worldwide, placing a huge burden
on health care resources. Although significant progress has been made in the development …

Modulating inflammatory macrophages with an apoptotic body-inspired nanoparticle

CA Kraynak, DJ Yan, LJ Suggs - Acta biomaterialia, 2020 - Elsevier
Macrophages play a critical role in the initiation, maintenance, and resolution of
inflammation because of their diverse and plastic phenotypic responses to extracellular …

Macrophage polarization in response to wear particles in vitro

JK Antonios, Z Yao, C Li, AJ Rao… - Cellular & molecular …, 2013 - nature.com
Total joint replacement is a highly successful surgical procedure for treatment of patients
with disabling arthritis and joint dysfunction. However, over time, with high levels of activity …

Folic acid conjugated chitosan for targeted delivery of siRNA to activated macrophages in vitro and in vivo

C Yang, S Gao, J Kjems - Journal of Materials Chemistry B, 2014 - pubs.rsc.org
Activated macrophages play an important role in the initiation and development of
inflammatory diseases. The aim of this study is to develop a delivery system that targets …

Click chemistry plays a dual role in biodegradable polymer design

J Guo, Z Xie, RT Tran, D Xie… - … materials (Deerfield Beach …, 2013 - pmc.ncbi.nlm.nih.gov
The need for soft and elastic scaffold materials to resemble the elastic nature of soft tissues
has recently driven the development of various biodegradable elastomeric polymers in …