Recent advancements in the targeted delivery of etoposide nanomedicine for cancer therapy: A comprehensive review

S Fathi-Karkan, R Arshad, A Rahdar… - European Journal of …, 2023 - Elsevier
Etoposide (ETO), a popular anticancer drug that inhibits topoisomerase II enzymes, may be
administered more effectively and efficiently due to nanomedicine. The therapeutic …

Triple negative breast cancer treatment options and limitations: future outlook

O Obidiro, G Battogtokh, EO Akala - Pharmaceutics, 2023 - mdpi.com
Triple negative breast cancer (TNBC) has a negative expression of estrogen receptors (ER),
progesterone receptors (PR), and human epidermal growth factor receptors (HER2). The …

The exit of nanoparticles from solid tumours

LNM Nguyen, ZP Lin, S Sindhwani, P MacMillan… - Nature Materials, 2023 - nature.com
Nanoparticles enter tumours through endothelial cells, gaps or other mechanisms, but how
they exit is unclear. The current paradigm states that collapsed tumour lymphatic vessels …

Perspectives for improving the tumor targeting of nanomedicine via the EPR effect in clinical tumors

J Kim, H Cho, DK Lim, MK Joo, K Kim - International journal of molecular …, 2023 - mdpi.com
Over the past few decades, the enhanced permeability and retention (EPR) effect of
nanomedicine has been a crucial phenomenon in targeted cancer therapy. Specifically …

Polymeric nanoparticles—Tools in a drug delivery system in selected cancer therapies

M Madej, N Kurowska, B Strzalka-Mrozik - Applied Sciences, 2022 - mdpi.com
The increase in cancer cases is undoubtedly affecting the development of new therapeutic
approaches. Polymeric nanoparticles are of great interest. Due to their relatively small size …

RGD-decorated PLGA nanoparticles improved effectiveness and safety of cisplatin for lung cancer therapy

B Yadav, M Chauhan, S Shekhar, A Kumar… - International Journal of …, 2023 - Elsevier
Upon extensive pharmaceutical and biomedical research to treat lung cancer indicates that
lung cancer remains one of the deadliest diseases and the leading cause of death in men …

Emerging applications of anti-angiogenic nanomaterials in oncotherapy

B Tang, W Ma, Y Lin - Journal of Controlled Release, 2023 - Elsevier
Angiogenesis is the process of generating new blood vessels from pre-existing vasculature.
Under normal conditions, this process is delicately controlled by pro-angiogenic and anti …

Biomolecule-protected gold nanoclusters: synthesis and biomedical applications

D Hao, X Zhang, R Su, Y Wang, W Qi - Journal of Materials Chemistry …, 2023 - pubs.rsc.org
Gold nanoclusters (AuNCs) consist of a few to several hundred gold atoms with a core size
of less than 2 nm. Gold nanoclusters are among the most stable metal nanoclusters and …

Recent progress of microneedles in transdermal immunotherapy: A review

X Ai, J Yang, Z Liu, T Guo, N Feng - International Journal of Pharmaceutics, 2024 - Elsevier
Since human skin is an immune organ, a large number of immune cells are distributed in the
epidermis and the dermis of the skin. Transdermal immunotherapy shows great therapeutic …

Nano-based drug delivery system for therapeutics: A comprehensive review

S Prakash - Biomedical Physics & Engineering Express, 2023 - iopscience.iop.org
Nanomedicine and nano-delivery systems hold unlimited potential in the developing
sciences, where nanoscale carriers are employed to efficiently deliver therapeutic drugs at …