Abstract Cryptolepine (1, 5-methyl-10 H-indolo [3, 2-b] quinoline), an indoloquinoline
alkaloid, found in the roots of Cryptolepis sanguinolenta (Lindl.) Schltr (family …

Malaria remains a global public health problem due to the uphill fight against the causative
Plasmodium parasites that are relentless in developing resistance. Indole-based …

Human babesiosis is a CDC reportable disease in the United States and is recognized as
an emerging health risk in multiple parts of the world. The current treatment for human …

The primary objective of this paper is to provide an evidence-based update of the literature
on the use of bioactive phytochemicals, nutraceuticals, and micronutrients (dietary …

Cryptolepine, the principal constituent of the West African climbing shrub Cryptolepis
sanguinolenta, continues to be of interest as a lead to new therapeutic agents, especially for …

Colorectal cancer (CRC) is the third most frequent cancer and the second leading cause of
cancer-related deaths globally. Evidence shows that over 90% of CRC cases are initiated by …

The drug resistance challenges in acute myeloid leukemia have been linked the hedgehog
(HH) signaling pathway activation by many studies. Furthermore, studies have shown that …

Abstract Cryptolepine (1, 5-methyl-10H-indolo [3, 2-b] quinoline), an indoloquinoline
alkaloid, found in the roots of Cryptolepis sanguinolenta (Lindl.) Schltr (family …

Scutellaria baicalensis, Alchornea cordifolia, and Polygonum cuspidatum to have good in
vitro inhibitory activity against B. duncani in the hamster erythrocyte model. Furthermore, we …

Evidence of Plasmodium resistance to some of the current antimalarial agents makes it
imperative to search for newer, and effective drugs to combat this challenge, and …