Introduction: Colorectal cancer (CRC) is one of the most common malignant tumors
worldwide and contributes significantly to cancer-related deaths. Since CRC is largely …

Developments in the diagnosis and treatment of colorectal cancer (CRC) have been made
in the last decade, but the overall survival rate of patients with CRC has not improved …

Background Histopathological assessment has a low potential to predict clinical outcome in
patients with the same stage of colorectal cancer. More specific and sensitive biomarkers to …

Background Identification of biomarkers associated with the prognosis of different cancer
subtypes is critical to achieve better therapeutic assistance. In colorectal cancer (CRC) the …

Colorectal cancer (CRC) is a major cause of global cancer mortality. Gene expression
profiles can help predict prognosis of patients with CRC. In most of previous studies, disease …

Dysregulated alternative splicing (AS) plays critical roles in driving cancer progression, and
the underlying mechanisms remain largely unknown. Here, we demonstrated that PHF5A, a …

Paeonol is a simple phenolic compound isolated from herbal root bark, which has been
reported to possess numerous biological and pharmacological characteristics, including a …

Background Clustering of gene expression data is widely used to identify novel subtypes of
cancer. Plenty of clustering approaches have been proposed, but there is a lack of …

Patient diagnosis and care would be significantly improved by understanding the
mechanisms underlying platinum and taxane resistance in ovarian cancer. Here, we aim to …

Identification of a potential gene signature for improved diagnosis in non-small cell lung
cancer (NSCLC) patient is necessary. Here, we aim to establish and validate the prognostic …