The age of anxiety: role of animal models of anxiolytic action in drug discovery

JF Cryan, FF Sweeney - British journal of pharmacology, 2011 - Wiley Online Library
Anxiety disorders are common, serious and a growing health problem worldwide. However,
the causative factors, aetiology and underlying mechanisms of anxiety disorders, as for most …

The neural mechanisms of gustation: a distributed processing code

SA Simon, IE de Araujo, R Gutierrez… - Nature Reviews …, 2006 - nature.com
Whenever food is placed in the mouth, taste receptors are stimulated. Simultaneously,
different types of sensory fibre that monitor several food attributes such as texture …

Functional internal complexity of amygdala: focus on gene activity mapping after behavioral training and drugs of abuse

E Knapska, K Radwanska, T Werka… - Physiological …, 2007 - journals.physiology.org
The amygdala is a heterogeneous brain structure implicated in processing of emotions and
storing the emotional aspects of memories. Gene activity markers such as c-Fos have been …

Identifying a network of brain regions involved in aversion-related processing: a cross-species translational investigation

DJ Hayes, G Northoff - Frontiers in integrative neuroscience, 2011 - frontiersin.org
The ability to detect and respond appropriately to aversive stimuli is essential for all
organisms, from fruit flies to humans. This suggests the existence of a core neural network …

Common brain activations for painful and non-painful aversive stimuli

DJ Hayes, G Northoff - BMC neuroscience, 2012 - Springer
Background Identification of potentially harmful stimuli is necessary for the well-being and
self-preservation of all organisms. However, the neural substrates involved in the processing …

Internal body state influences topographical plasticity of sensory representations in the rat gustatory cortex

R Accolla, A Carleton - … of the National Academy of Sciences, 2008 - National Acad Sciences
Primary sensory cortices are remarkably organized in spatial maps according to specific
sensory features of the stimuli. These cortical maps can undergo plastic rearrangements …

A physiological increase of insulin in the olfactory bulb decreases detection of a learned aversive odor and abolishes food odor-induced sniffing behavior in rats

P Aime, C Hegoburu, T Jaillard, C Degletagne… - PLoS …, 2012 - journals.plos.org
Insulin is involved in multiple regulatory mechanisms, including body weight and food
intake, and plays a critical role in metabolic disorders such as obesity and diabetes. An …

Taste and odor recognition memory: the emotional flavor of life

MI Miranda - Reviews in the Neurosciences, 2012 - degruyter.com
In recent years, our knowledge of the neurobiology of taste and smell has greatly increased;
by using several learning models, we now have a better understanding of the behavioral …

Conditioned taste aversions

KC Chambers - Handbook of olfaction and gustation, 2015 - Wiley Online Library
Conditioned taste aversions (CTAs) are those that develop on the basis of experience with a
food or drink. The experience on which such aversions are based is often the consumption …

Taste memory formation: latest advances and challenges

L Núñez-Jaramillo, L Ramírez-Lugo… - Behavioural brain …, 2010 - Elsevier
Taste memory has been a useful model for studying memory formation; using different
approaches ranging from lesion studies, analysis of receptor and neurotransmitter activity …