Replication-coupled nucleosome assembly in the passage of epigenetic information and cell identity
A Serra-Cardona, Z Zhang - Trends in biochemical sciences, 2018 - cell.com
During S phase, replicated DNA must be assembled into nucleosomes using both newly
synthesized and parental histones in a process that is tightly coupled to DNA replication …
synthesized and parental histones in a process that is tightly coupled to DNA replication …
H3–H4 histone chaperone pathways
Nucleosomes compact and organize genetic material on a structural level. However, they
also alter local chromatin accessibility through changes in their position, through the …
also alter local chromatin accessibility through changes in their position, through the …
Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1
Chromatin inheritance entails de novo nucleosome assembly after DNA replication by
chromatin assembly factor-1 (CAF-1). Yet direct knowledge about CAF-1's histone binding …
chromatin assembly factor-1 (CAF-1). Yet direct knowledge about CAF-1's histone binding …
CAF-1 deposits newly synthesized histones during DNA replication using distinct mechanisms on the leading and lagging strands
C Rouillon, BV Eckhardt, L Kollenstart… - Nucleic acids …, 2023 - academic.oup.com
During every cell cycle, both the genome and the associated chromatin must be accurately
replicated. Chromatin Assembly Factor-1 (CAF-1) is a key regulator of chromatin replication …
replicated. Chromatin Assembly Factor-1 (CAF-1) is a key regulator of chromatin replication …
Mechanistic insights into histone deposition and nucleosome assembly by the chromatin assembly factor-1
Eukaryotic chromatin is a highly dynamic structure with essential roles in virtually all DNA-
dependent cellular processes. Nucleosomes are a barrier to DNA access, and during DNA …
dependent cellular processes. Nucleosomes are a barrier to DNA access, and during DNA …
The histone chaperoning pathway: from ribosome to nucleosome
AJ Pardal, F Fernandes-Duarte… - Essays in …, 2019 - portlandpress.com
Nucleosomes represent the fundamental repeating unit of eukaryotic DNA, and comprise
eight core histones around which DNA is wrapped in nearly two superhelical turns. Histones …
eight core histones around which DNA is wrapped in nearly two superhelical turns. Histones …
DNA-mediated association of two histone-bound complexes of yeast Chromatin Assembly Factor-1 (CAF-1) drives tetrasome assembly in the wake of DNA replication
Nucleosome assembly in the wake of DNA replication is a key process that regulates cell
identity and survival. Chromatin assembly factor 1 (CAF-1) is a H3-H4 histone chaperone …
identity and survival. Chromatin assembly factor 1 (CAF-1) is a H3-H4 histone chaperone …
Homeostatic nuclear RAGE–ATM interaction is essential for efficient DNA repair
The integrity of genome is a prerequisite for healthy life. Indeed, defects in DNA repair have
been associated with several human diseases, including tissue-fibrosis, neurodegeneration …
been associated with several human diseases, including tissue-fibrosis, neurodegeneration …
The replisome guides nucleosome assembly during DNA replication
W Zhang, J Feng, Q Li - Cell & bioscience, 2020 - Springer
Nucleosome assembly during DNA replication is tightly coupled to ongoing DNA synthesis.
This process, termed DNA replication-coupled (RC) nucleosome assembly, is essential for …
This process, termed DNA replication-coupled (RC) nucleosome assembly, is essential for …
The Cac1 subunit of histone chaperone CAF-1 organizes CAF-1-H3/H4 architecture and tetramerizes histones
The histone chaperone Chromatin Assembly Factor 1 (CAF-1) deposits tetrameric (H3/H4) 2
histones onto newly-synthesized DNA during DNA replication. To understand the …
histones onto newly-synthesized DNA during DNA replication. To understand the …