How do plants defend themselves against pathogens-Biochemical mechanisms and genetic interventions

S Kaur, MK Samota, M Choudhary… - … and Molecular Biology …, 2022 - Springer
In agro-ecosystem, plant pathogens hamper food quality, crop yield, and global food
security. Manipulation of naturally occurring defense mechanisms in host plants is an …

[HTML][HTML] Is melatonin the cornucopia of the 21st century?

N Ferlazzo, G Andolina, A Cannata, MG Costanzo… - Antioxidants, 2020 - mdpi.com
Melatonin, an indoleamine hormone produced and secreted at night by pinealocytes and
extra-pineal cells, plays an important role in timing circadian rhythms (24-h internal clock) …

Functions of melatonin in plants: a review

MB Arnao, J Hernández‐Ruiz - Journal of pineal research, 2015 - Wiley Online Library
The number of studies on melatonin in plants has increased significantly in recent years.
This molecule, with a large set of functions in animals, has also shown great potential in …

Melatonin function and crosstalk with other phytohormones under normal and stressful conditions

M Khan, S Ali, H Manghwar, S Saqib, F Ullah, A Ayaz… - Genes, 2022 - mdpi.com
Melatonin was discovered in plants in the late nineties, but its role, signaling, and crosstalk
with other phytohormones remain unknown. Research on melatonin in plants has risen …

Melatonin: buffering the immune system

A Carrillo-Vico, PJ Lardone… - International journal of …, 2013 - mdpi.com
Melatonin modulates a wide range of physiological functions with pleiotropic effects on the
immune system. Despite the large number of reports implicating melatonin as an …

Melatonin and its protective role against biotic stress impacts on plants

M Moustafa-Farag, A Almoneafy, A Mahmoud… - Biomolecules, 2019 - mdpi.com
Biotic stress causes immense damage to agricultural products worldwide and raises the risk
of hunger in many areas. Plants themselves tolerate biotic stresses via several pathways …

Melatonin mediates mucosal immune cells, microbial metabolism, and rhythm crosstalk: a therapeutic target to reduce intestinal inflammation

N Ma, J Zhang, RJ Reiter, X Ma - Medicinal Research Reviews, 2020 - Wiley Online Library
Nowadays, melatonin, previously considered only as a pharmaceutical product for rhythm
regulation and sleep aiding, has shown its potential as a co‐adjuvant treatment in intestinal …

The changing biological roles of melatonin during evolution: from an antioxidant to signals of darkness, sexual selection and fitness

DX Tan, R Hardeland, LC Manchester… - Biological …, 2010 - Wiley Online Library
Melatonin is a molecule present in a multitude of taxa and may be ubiquitous in organisms. It
has been found in bacteria, unicellular eukaryotes, macroalgae, fungi, plants and animals. A …

Phytomelatonin as a central molecule in plant disease resistance

H Zeng, Y Bai, Y Wei, RJ Reiter… - Journal of Experimental …, 2022 - academic.oup.com
Melatonin is an essential phytohormone in the regulation of many plant processes, including
during plant development and in response to stress. Pathogen infections cause serious …

Clinical uses of melatonin: evaluation of human trials

EJ Sánchez-Barceló, MD Mediavilla… - Current medicinal …, 2010 - ingentaconnect.com
During the last 20 years, numerous clinical trials have examined the therapeutic usefulness
of melatonin in different fields of medicine. The objective of this article is to review, in depth …