The recent advances in nucleophilic fluorination, regulated through hydrogen bonding
interactions are summarized. Two main categories of fluorine nucleophiles are discussed …

Fluorinated compounds act as a link between synthetic organic chemistry and medicinal
chemistry and compel researchers to explore modified and innovative methods for the …

Anion coordination chemistry using O–H groups - Chemical Society Reviews (RSC
Publishing) DOI:10.1039/C8CS00828K Royal Society of Chemistry View PDF VersionPrevious …

An unbalanced ion pair promoter (eg, tetrabutylammonium sulfate), consisting of a bulky and
charge-delocalized cation and a small and charge-localized anion, greatly accelerates …

Ionic reactions have an important solvent effect and the first solvation shell makes the most
important contribution for determining the reactivity. In the case of nucleophilic fluorination …

The benefits of fluorine incorporation into biologically active molecules are well
documented, and, at the current time, approximately 25% of pharmaceuticals on the market …

Activation of potassium fluoride salt for selective and fast nucleophilic fluorination requires
its solubilization and stabilization of the respective transition state. This goal can be …

Fluorinated arenes play a crucial role in drug discovery, specialty materials, and medical
imaging. Although several variants for Cu‐mediated nucleophilic fluorination of arylboronic …

The 18F syntheses of tracers for positron emission tomography (PET) typically require
several steps, including extraction of [18F] fluoride from H2 [18O] O, elution, and drying, prior …

The hydroxyl group was discovered to promote gold catalyzed hydrofluorination of alkynes
via hydrogen bonding interaction. Based on this strategy, propargyl alcohols could be …