Kratom—pharmacology, clinical implications, and outlook: a comprehensive review
SC Eastlack, EM Cornett, AD Kaye - Pain and therapy, 2020 - Springer
Kratom, or Mitragyna, is a tropical plant indigenous to Southeast Asia, with unique
pharmacological properties. It is commonly consumed by preparing the leaves into …
pharmacological properties. It is commonly consumed by preparing the leaves into …
Understanding kratom use: a guide for healthcare providers
Kratom (Mitragyna speciosa Korth., Rubiaceae) is a plant native to Southeast Asia, where it
has been used for centuries as a mild stimulant and as medicine for various ailments. More …
has been used for centuries as a mild stimulant and as medicine for various ailments. More …
Chemical composition and biological effects of kratom (Mitragyna speciosa): In vitro studies with implications for efficacy and drug interactions
The safety and efficacy of kratom (Mitragyna speciosa) for treatment of pain is highly
controversial. Kratom produces more than 40 structurally related alkaloids, but most studies …
controversial. Kratom produces more than 40 structurally related alkaloids, but most studies …
Current perspectives on the impact of Kratom use
C Veltri, O Grundmann - Substance abuse and rehabilitation, 2019 - Taylor & Francis
The leaves from the tree Mitragyna speciosa, commonly known as Kratom, in the coffee
plant family (Rubiaceae) are commonly used in their native habitat of Southeast Asia as a …
plant family (Rubiaceae) are commonly used in their native habitat of Southeast Asia as a …
Kratom as a substitute for opioids: results from an online survey
MA Coe, JL Pillitteri, MA Sembower, KK Gerlach… - Drug and alcohol …, 2019 - Elsevier
Abstract Background Kratom is a South Eastern Asian tree whose leaves are used to make
tea-like brews or swallowed in powdered form for various health and well-being reasons …
tea-like brews or swallowed in powdered form for various health and well-being reasons …
Activity of Mitragyna speciosa (“Kratom”) Alkaloids at Serotonin Receptors
Kratom alkaloids have mostly been evaluated for their opioid activity but less at other targets
that could contribute to their physiological effects. Here, we investigated the in vitro and in …
that could contribute to their physiological effects. Here, we investigated the in vitro and in …
Characteristics of deaths associated with kratom use
JM Corkery, P Streete, H Claridge… - Journal of …, 2019 - journals.sagepub.com
Background: Kratom (Mitragyna speciosa Korth) use has increased in Western countries,
with a rising number of associated deaths. There is growing debate about the involvement of …
with a rising number of associated deaths. There is growing debate about the involvement of …
Therapeutic benefit with caveats?: Analyzing social media data to understand the complexities of kratom use
Background Mitragyna speciosa, referred to as “kratom”, is increasingly used in the United
States for self-treating pain, psychiatric, and substance use disorder symptoms. It is used by …
States for self-treating pain, psychiatric, and substance use disorder symptoms. It is used by …
Prevalence and motivations for kratom use in a sample of substance users enrolled in a residential treatment program
Background Kratom use in the West has increased recently, yet the prevalence and motives
for use among individuals with a history of substance use disorder (SUD) have not been fully …
for use among individuals with a history of substance use disorder (SUD) have not been fully …
Oxidative metabolism as a modulator of kratom's biological actions
S Chakraborty, R Uprety, ST Slocum, T Irie… - Journal of medicinal …, 2021 - ACS Publications
The leaves of Mitragyna speciosa (kratom), a plant native to Southeast Asia, are increasingly
used as a pain reliever and for attenuation of opioid withdrawal symptoms. Using the tools of …
used as a pain reliever and for attenuation of opioid withdrawal symptoms. Using the tools of …