Superoxide dismutase administration: A review of proposed human uses

AC Rosa, D Corsi, N Cavi, N Bruni, F Dosio - Molecules, 2021 - mdpi.com
Superoxide dismutases (SODs) are metalloenzymes that play a major role in antioxidant
defense against oxidative stress in the body. SOD supplementation may therefore trigger the …

Dissecting copper biology and cancer treatment:'Activating Cuproptosis or suppressing Cuproplasia'

Y Yang, M Li, G Chen, S Liu, H Guo, X Dong… - Coordination Chemistry …, 2023 - Elsevier
Copper, an essential micronutrient, controls multiple fundamental processes throughout all
forms of life, such as respiration, cell proliferation and neurotransmitter biosynthesis. High …

[HTML][HTML] Mechanisms of SOD1 regulation by post-translational modifications

CJ Banks, JL Andersen - Redox biology, 2019 - Elsevier
SOD1 is commonly known for its ROS scavenging activity, but recent work has uncovered
additional roles in modulating metabolism, maintaining redox balance, and regulating …

Proteomics revealed the crosstalk between copper stress and cuproptosis, and explored the feasibility of curcumin as anticancer copper ionophore

Y Yang, S Liang, H Geng, M Xiong, M Li, Q Su… - Free Radical Biology …, 2022 - Elsevier
As an essential micronutrient element in organisms, copper controls a host of fundamental
cellular functions. Recently, copper-dependent cell growth and proliferation have been …

Nuclear SOD1 in growth control, oxidative stress response, amyotrophic lateral sclerosis, and cancer

J Xu, X Su, SK Burley, XFS Zheng - Antioxidants, 2022 - mdpi.com
SOD1 is the major superoxide dismutase responsible for catalyzing dismutation of
superoxide to hydrogen peroxide and molecular oxygen. It is well known as an essential …

[HTML][HTML] Multifunctional role of zinc in human health: an update

DP Kiouri, E Tsoupra, M Peana, SP Perlepes… - EXCLI …, 2023 - ncbi.nlm.nih.gov
Zinc is a multipurpose trace element for the human body, as it plays a crucial part in various
physiological processes, such as cell growth and development, metabolism, cognitive …

Copper nutrition and biochemistry and human (patho) physiology

JF Collins - Advances in food and nutrition research, 2021 - Elsevier
The essential trace mineral copper plays important roles in human physiology and
pathophysiology. Disruption of copper homeostasis may underlie the development of …

Insights on the effects of resveratrol and some of its derivatives in cancer and autoimmunity: a molecule with a dual activity

E Gianchecchi, A Fierabracci - Antioxidants, 2020 - mdpi.com
In recent years, the interest in natural compounds exerting immunoregulatory effects has
enormously increased. Among these, the polyphenol resveratrol, found in a variety of foods …

Metal complexes or chelators with ROS regulation capacity: Promising candidates for cancer treatment

X Li, Y Wang, M Li, H Wang, X Dong - Molecules, 2021 - mdpi.com
Reactive oxygen species (ROS) are rapidly eliminated and reproduced in organisms, and
they always play important roles in various biological functions and abnormal pathological …

Modulation of superoxide dismutase activity by mercury, lead, and arsenic

A Kumar, Khushboo, R Pandey, B Sharma - Biological trace element …, 2020 - Springer
Arsenic, mercury and lead are the environmental toxicants which exert their toxic effects
through binding with certain proteins including their structures and functions. The toxicity of …