Hyaluronic acid-based nanosystems for CD44 mediated anti-inflammatory and antinociceptive activity

S Salathia, MR Gigliobianco, C Casadidio… - International Journal of …, 2023 - mdpi.com
The nervous and immune systems go hand in hand in causing inflammation and pain.
However, the two are not mutually exclusive. While some diseases cause inflammation …

[HTML][HTML] Nano drug delivery in intracellular bacterial infection treatments

SM Hosseini, M Taheri, F Nouri, A Farmani… - Biomedicine & …, 2022 - Elsevier
The present work aimed to review the potential mechanisms used by macrophages to kill
intracellular bacteria, their entrance to the cell, and mechanisms of escape of cellular …

Tuning macrophages for atherosclerosis treatment

F Fang, C Xiao, C Li, X Liu, S Li - Regenerative Biomaterials, 2023 - academic.oup.com
Atherosclerosis is a chronic inflammatory vascular disease and a leading cause of death
worldwide. Macrophages play an important role in inflammatory responses, cell–cell …

Chitosan biopolymer, its derivatives and potential applications in nano-therapeutics: A comprehensive review

M Mukhtar, E Fényes, C Bartos, M Zeeshan… - European Polymer …, 2021 - Elsevier
Chitosan (CS) is a natural biopolymer used frequently in drug delivery because of its
biodegradability and biocompatibility. Several derivatives of CS have also been synthesized …

Development, in vitro and in vivo evaluation of miltefosine loaded nanostructured lipid carriers for the treatment of Cutaneous Leishmaniasis

AS Khan, F ud Din, Z Ali, M Bibi, F Zahid, A Zeb… - International journal of …, 2021 - Elsevier
The purpose of this study was to enhance the anti-leishmanial efficacy of miltefosine (MTF)
and reduce its toxic effects by loading it into nanostructured lipid carriers (NLCs). Micro …

Transdermal drug delivery via microneedles for musculoskeletal systems

H Zheng, X Xie, H Ling, X You, S Liang, R Lin… - Journal of Materials …, 2023 - pubs.rsc.org
As the population is ageing and lifestyle is changing, the prevalence of musculoskeletal
(MSK) disorders is gradually increasing with each passing year, posing a serious threat to …

The role of macrophages in atherosclerosis: pathophysiologic mechanisms and treatment considerations

P Theofilis, E Oikonomou, K Tsioufis… - International Journal of …, 2023 - mdpi.com
Atherosclerotic diseases are a leading cause of morbidity and mortality worldwide, despite
the recent diagnostic and therapeutic advances. A thorough understanding of the …

Emerging insights of peptide-based nanotherapeutics for effective management of rheumatoid arthritis

V Pathade, S Nene, S Ratnam, DK Khatri… - Life Sciences, 2023 - Elsevier
Rheumatoid arthritis (RA) is a chronic, prevalent, immune-mediated, inflammatory, joint
disorder affecting millions of people worldwide. Despite current treatment options, many …

Nanodiagnosis and nanotreatment of cardiovascular diseases: An overview

F Sabir, M Barani, M Mukhtar, A Rahdar, M Cucchiarini… - Chemosensors, 2021 - mdpi.com
Cardiovascular diseases (CVDs) are the world's leading cause of mortality and represent a
large contributor to the costs of medical care. Although tremendous progress has been …

Aerodynamic properties and in silico deposition of isoniazid loaded chitosan/thiolated chitosan and hyaluronic acid hybrid nanoplex DPIs as a potential TB treatment

M Mukhtar, E Pallagi, I Csóka, E Benke… - International Journal of …, 2020 - Elsevier
Existing therapies yield low drug encapsulation or accumulation in the lungs, hence the site-
specific drug delivery remains the challenge for tuberculosis. Lately, dry powder inhalers …