Astrocytes contribute to the maintenance of the health and function of the central nervous
system (CNS). Thus, it is not surprising that these multifunctional cells have been implicated …

In recent years, previously unsuspected roles of astrocytes have been revealed, largely
owing to the development of new tools enabling their selective study in situ. These exciting …

The term neurodegenerative disease refers to the principal pathology associated with
disorders such as amyotrophic lateral sclerosis, Alzheimer's disease, Huntington's disease …

Purpose: It is generally accepted that blood–brain barrier (BBB) failure occurs as a result of
CNS diseases, including epilepsy. However, evidences also suggest that BBB failure may …

Autosomal‐dominant spinocerebellar ataxias, autosomal‐recessive spinocerebellar ataxias,
and hereditary spastic paraplegias have traditionally been designated in separate …

The inability of the mammalian central nervous system (CNS) to undergo spontaneous
regeneration has long been regarded as a central tenet of neurobiology. However, although …

1The past decade has witnessed a burst of speculation and data about how astrocyte
dysfunction contributes to the phenotypes of the well known neurodegenerative diseases …

Diseases of the human brain are almost universally attributed to malfunction or loss of nerve
cells. However, a considerable amount of work has, during the last decade, expanded our …

The various forms of tremor are now classified in two axes: clinical characteristics (axis 1)
and etiology (axis 2). Electrophysiology is an extension of the clinical exam …

Background The cellular mechanism (s) underlying autism spectrum disorders (ASDs) are
not completely understood, but ASDs are thought to ultimately result from disrupted …