[HTML][HTML] Overrunning in clinical trials: some thoughts from a methodological review
Background In sequential and adaptive trials, the delay that happens after the trial is
stopped, by a predetermined stopping criterion, takes the name of overrunning. Overrunning …
stopped, by a predetermined stopping criterion, takes the name of overrunning. Overrunning …
Variance prior specification for a basket trial design using Bayesian hierarchical modeling
Background: In the era of targeted therapies, clinical trials in oncology are rapidly evolving,
wherein patients from multiple diseases are now enrolled and treated according to their …
wherein patients from multiple diseases are now enrolled and treated according to their …