Nonenzymatic reactions in natural product formation

LM Bouthillette, V Aniebok, DA Colosimo… - Chemical …, 2022 - ACS Publications
Biosynthetic mechanisms of natural products primarily depend on systems of protein
catalysts. However, within the field of biosynthesis, there are cases in which the inherent …

Synthesis of High-Order and High-Oxidation State Securinega Alkaloids

G Kang, S Park, S Han - Accounts of Chemical Research, 2023 - ACS Publications
Conspectus Securinega alkaloids, composed of more than 100 members characterized by
the compact tetracyclic scaffold, have fascinated the synthetic community with their structural …

Indigenous uses, phytochemical analysis, and anti-inflammatory properties of Australian tropical medicinal plants

K Yeshi, G Turpin, T Jamtsho, P Wangchuk - Molecules, 2022 - mdpi.com
Australian tropical plants have been a rich source of food (bush food) and medicine to the
first Australians (Aboriginal people), who are believed to have lived for more than 50,000 …

Novel monoamine oxidase inhibitors: a patent review (2012–2014)

S Carradori, JP Petzer - Expert opinion on therapeutic patents, 2015 - Taylor & Francis
Introduction: Monoamine oxidase (MAO) inhibitors, despite the initial pharmacological
interest, are used in clinic for their antidepressant effect and in the management of …

Eurifoloids A–R, Structurally Diverse Diterpenoids from Euphorbia neriifolia

JX Zhao, CP Liu, WY Qi, ML Han, YS Han… - Journal of Natural …, 2014 - ACS Publications
Eighteen new diterpenoids, named eurifoloids A–R (1–18), including ingenane (1 and 2),
abietane (3–7), isopimarane (8–12), and ent-atisane (13–18) types, along with four known …

The structure and bioactivities of Stemona alkaloids and alkaloids with [1,2-α] azepine nucleus (2009–2021)

Y Xu, J Liang, Y Yan, D Sun, H Li, L Chen - Phytochemistry Reviews, 2024 - Springer
Stemona alkaloids with a unique skeleton of pyrrolo [1, 2-a] azepine, pyrido [1, 2-a] azepine,
pyrido [1, 2-a] azonine or indolizidine core are obtained only from the Stemonaceae family …

The securinega alkaloids

E Chirkin, W Atkatlian, FH Porée - The alkaloids: chemistry and biology, 2015 - Elsevier
Securinega alkaloids represent a family of plant secondary metabolites known for 50 years.
Securinine (1), the most abundant and studied alkaloid of this series was isolated by …

An accelerated intermolecular Rauhut–Currier reaction enables the total synthesis of (−)-flueggenine C

S Jeon, S Han - Journal of the American Chemical Society, 2017 - ACS Publications
The first total synthesis of dimeric securinega alkaloid (−)-flueggenine C is completed via an
accelerated intermolecular Rauhut–Currier (RC) reaction. Despite the numerous reports on …

Flueggeacosines A–C, Dimeric Securinine-Type Alkaloid Analogues with Neuronal Differentiation Activity from Flueggea suffruticosa

ZL Wu, XJ Huang, MT Xu, X Ma, L Li, L Shi… - Organic …, 2018 - ACS Publications
Flueggeacosines A–C (1–3), three dimeric securinine-type alkaloid analogues with
unprecedented skeletons, were isolated from Flueggea suffruticosa. Compounds 1 and 2 …

Traditional Uses, Pharmacology and Phytochemistry of the Medicinal Plant Flueggea virosa (Roxb. ex Willd.) Royle

C Bailly - Future Pharmacology, 2024 - mdpi.com
The white berry bush, officially Flueggea virosa (Roxb. ex Willd.) Royle is a medicinal plant
distributed throughout tropical areas and traditionally used in Africa, India and China. Root …