Depression and obesity: evidence of shared biological mechanisms

Y Milaneschi, WK Simmons, EFC van Rossum… - Molecular …, 2019 - nature.com
Depression and obesity are common conditions with major public health implications that
tend to co-occur within individuals. The relationship between these conditions is …

Metabolic syndrome in psychiatric patients: overview, mechanisms, and implications

BWJH Penninx, SMM Lange - Dialogues in clinical neuroscience, 2018 - Taylor & Francis
Psychiatric patients have a greater risk of premature mortality, predominantly due to
cardiovascular diseases (CVDs). Convincing evidence shows that psychiatric conditions are …

[HTML][HTML] Obesity and depression: its prevalence and influence as a prognostic factor: a systematic review

BV Blasco, J García-Jiménez, I Bodoano… - Psychiatry …, 2020 - ncbi.nlm.nih.gov
Objective Depression and obesity are two conditions with great impact over global health.
This is mainly due to their high prevalence and the morbidity and mortality associated to …

Depression and cardiovascular disease: epidemiological evidence on their linking mechanisms

BWJH Penninx - Neuroscience & Biobehavioral Reviews, 2017 - Elsevier
Depression's burden of disease goes beyond functioning and quality of life and extends to
somatic health. Results from longitudinal cohort studies converge in illustrating that major …

Depression heterogeneity and its biological underpinnings: toward immunometabolic depression

Y Milaneschi, F Lamers, M Berk, BWJH Penninx - Biological psychiatry, 2020 - Elsevier
Epidemiological evidence indicates the presence of dysregulated homeostatic biological
pathways in depressed patients, such as increased inflammation and disrupted energy …

The interface of depression and obesity

N Jantaratnotai, K Mosikanon, Y Lee… - Obesity research & clinical …, 2017 - Elsevier
Depression and obesity are both highly prevalent and are leading public health problems.
These foregoing disorders independently have great impact on morbidity and mortality …

Emotional eating as a mediator between depression and weight gain

T van Strien, H Konttinen, JR Homberg, RCME Engels… - Appetite, 2016 - Elsevier
Depression is often associated with weight gain but underlying mechanisms are unclear.
This study assessed whether three psychological eating styles (emotional eating, external …

Gut microbiota, bacterial translocation, and interactions with diet: pathophysiological links between major depressive disorder and non-communicable medical …

A Slyepchenko, M Maes, FN Jacka, CA Köhler… - Psychotherapy and …, 2016 - karger.com
Background: Persistent low-grade immune-inflammatory processes, oxidative and
nitrosative stress (O&NS), and hypothalamic-pituitary-adrenal axis activation are integral to …

Insulin resistance in depression: A large meta-analysis of metabolic parameters and variation

BS Fernandes, E Salagre, N Enduru, I Grande… - Neuroscience & …, 2022 - Elsevier
Increased insulin resistance is recognized in psychiatric disorders, such as schizophrenia
and bipolar disorder, but its occurrence in depression is less clear. Our aims were to verify if …

[HTML][HTML] High-fat diet enhances working memory in the Y-maze test in male C57BL/6J mice with less anxiety in the elevated plus maze test

K Yoshizaki, M Asai, T Hara - Nutrients, 2020 - mdpi.com
Obesity is characterized by massive adipose tissue accumulation and is associated with
psychiatric disorders and cognitive impairment in human and animal models. However, it is …