The intestinal microbiota determines immune responses against extraintestinal antigens,
including tumor-associated antigens. Indeed, depletion or gross perturbation of the …

Cancer dissemination to lymph nodes (LN) is associated with a worse prognosis, increased
incidence of distant metastases and reduced response to therapy. The LN microenvironment …

Edible offal of farmed animals can accumulate cadmium (Cd). However, no studies have
investigated Cd bioavailability and its health effects. Here, based on mouse models, market …

Tremendous progress has been made in improving cancer immunotherapy, which is now
established as a pillar for cancer treatment. Immune checkpoint inhibitors (ICIs) enhance …

This article reports the results of an ecological study of cancer incidence rates by state in the
US for the period 2016–2020. The goals of this study were to determine the extent to which …

The antitumor immune response plays a crucial role in successful cancer treatment. In a
recent article in Science, Giampazolias et al.[1] reported a vitamin D (VitD)-mediated …

Several studies have indicated that 1α, 25-hydroxyvitamin D [1α, 25 (OH) 2 D 3] inhibits the
proliferation and metastasis of cancer cells through suppressing epithelial-mesenchymal …

Classically, vitamin D is known to regulate skeletal and mineral ion homeostasis. The active
form of vitamin D, 1α, 25-dihydroxyvitamin D3 [1, 25 (OH) 2D3], binds with high affinity to the …

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer without effective
treatments. It is characterized by activating KRAS mutations and p53 alterations. However …

Vitamin D has a role in immune modulation and in shaping commensal microbial
communities. Reis e Sousa and colleagues show that mice lacking Gc globulin (Gc …