Objective To update evidence‐based medicine recommendations for treating nonmotor
symptoms in Parkinson's disease (PD). Background The International Parkinson and …

Functional dyspepsia is a common functional gastrointestinal (GI) disorder of
gastroduodenal origin, diagnosed clinically in the presence of prototypical symptoms of …

Drug safety initiatives have endorsed human iPSC-derived cardiomyocytes (hiPSC-CMs) as
an in vitro model for predicting drug-induced cardiac arrhythmia. However, the extent to …

A central goal of the Academy of Breastfeeding Medicine is the development of clinical
protocols for managing common medical problems that may impact breastfeeding success …

The human ether-a-go-go (hERG) potassium channel (K v 11. 1) plays a critical role in
mediating cardiac action potential. The blockade of this ion channel can potentially lead fatal …

Up to 40% of patients report persistent gastroesophageal reflux disease (GERD) symptoms
despite proton pump inhibitor (PPI) therapy. This review outlines the evidence for medical …

Systemic sclerosis (SSc) is a multisystemic autoimmune connective tissue disorder; in the
gastrointestinal tract, the esophagus is the most commonly affected organ. Symptoms of …

Background There is increased awareness about risks and benefits of using domperidone to
treat gastroparesis. Aim To describe the outcome of treating patients with refractory …

Aims Concerns exist regarding the cardiovascular safety of domperidone. However, many of
the previous studies addressing this issue had important limitations. We aimed to examine …

Esophageal hypomotility in general and especially ineffective esophageal motility according
to the Chicago criteria of primary motility disorders of the esophagus, is one of the most …