Brain metastases are one of the most common neurologic complications of cancer. The
incidence is 9%–17% based on various studies, although the exact incidence is thought to …

The advent of HER2-directed therapies has significantly improved the outlook for patients
with HER2-positive early stage breast cancer. However, a significant proportion of these …

This review examines the relationship between physical activity and cancer along the
cancer continuum, and serves as a synthesis of systematic and meta-analytic reviews …

Background Metastatic breast cancer (MBC) behaviour differs depending on hormone
receptors (HR) and human epidermal growth factor receptor (HER2) statuses. Methods The …

Answer questions and earn CME/CNE Advances in genomics and molecular biology have
identified aberrant proteins in cancer cells that are attractive targets for cancer therapy …

Objectives: The purpose of this study was to estimate heart failure (HF) and cardiomyopathy
(CM) rates after adjuvant trastuzumab therapy and chemotherapy in a population of older …

Objectives This study sought to assess the effects of neurohormonal therapies in preventing
cardiotoxicity in patients receiving chemotherapy. Background Various cardioprotective …

Molecularly targeted cancer therapies, such as small-molecule kinase inhibitors and
monoclonal antibodies, constitute a rapidly growing and an important part of the oncology …

The incidence of metastasis to the brain is apparently rising in cancer patients and threatens
to limit the gains that have been made by new systemic treatments. The brain is considered …

Breast cancer (BC) is a highly prevalent disease, accounting for the second highest number
of cancer-related mortalities worldwide. The anthracycline doxorubicin (DOX), isolated from …