The role of MicroRNAs in human cancer
Y Peng, CM Croce - Signal transduction and targeted therapy, 2016 - nature.com
MicroRNAs (miRNAs) are endogenous, small non-coding RNAs that function in regulation of
gene expression. Compelling evidences have demonstrated that miRNA expression is …
gene expression. Compelling evidences have demonstrated that miRNA expression is …
Immunomodulatory effects of green tea polyphenols
Green tea and its bioactive components, especially polyphenols, possess many health-
promoting and disease-preventing benefits, especially anti-inflammatory, antioxidant …
promoting and disease-preventing benefits, especially anti-inflammatory, antioxidant …
YTHDF2 orchestrates tumor-associated macrophage reprogramming and controls antitumor immunity through CD8+ T cells
Despite tumor-associated macrophages (TAMs) playing a key role in shaping the tumor
microenvironment (TME), the mechanisms by which TAMs influence the TME and contribute …
microenvironment (TME), the mechanisms by which TAMs influence the TME and contribute …
CAR-engineered NK cells targeting wild-type EGFR and EGFRvIII enhance killing of glioblastoma and patient-derived glioblastoma stem cells
J Han, J Chu, W Keung Chan, J Zhang, Y Wang… - Scientific reports, 2015 - nature.com
Glioblastoma (GB) remains the most aggressive primary brain malignancy. Adoptive transfer
of chimeric antigen receptor (CAR)-modified immune cells has emerged as a promising anti …
of chimeric antigen receptor (CAR)-modified immune cells has emerged as a promising anti …
CS1-specific chimeric antigen receptor (CAR)-engineered natural killer cells enhance in vitro and in vivo antitumor activity against human multiple myeloma
Multiple myeloma (MM) is an incurable hematological malignancy. Chimeric antigen
receptor (CAR)-expressing T cells have been demonstrated successfully in the clinic to treat …
receptor (CAR)-expressing T cells have been demonstrated successfully in the clinic to treat …
Recent trends in targeting miRNAs for cancer therapy
Objectives MicroRNAs (miRNAs) are a type of small noncoding RNA employed by the cells
for gene regulation. A single miRNA, typically 22 nucleotides in length, can regulate the …
for gene regulation. A single miRNA, typically 22 nucleotides in length, can regulate the …
Noncoding RNAs in cancer immunity: functions, regulatory mechanisms, and clinical application
L Zhang, X Xu, X Su - Molecular cancer, 2020 - Springer
It is well acknowledged that immune system is deeply involved in cancer initiation and
progression, and can exert both pro-tumorigenic and anti-tumorigenic effects, depending on …
progression, and can exert both pro-tumorigenic and anti-tumorigenic effects, depending on …
[PDF][PDF] let-7 MicroRNAs regulate microglial function and suppress glioma growth through toll-like receptor 7
Microglia express Toll-like receptors (TLRs) that sense pathogen-and host-derived factors,
including single-stranded RNA. In the brain, let-7 microRNA (miRNA) family members are …
including single-stranded RNA. In the brain, let-7 microRNA (miRNA) family members are …
Trial Watch: Toll-like receptor agonists for cancer therapy
E Vacchelli, A Eggermont, C Sautès-Fridman… - …, 2013 - Taylor & Francis
Toll-like receptors (TLRs) have long been known for their ability to initiate innate immune
responses upon exposure to conserved microbial components such as lipopolysaccharide …
responses upon exposure to conserved microbial components such as lipopolysaccharide …
Adipose-derived mesenchymal stromal cells in basic research and clinical applications
K Czerwiec, M Zawrzykraj, M Deptuła… - International Journal of …, 2023 - mdpi.com
Adipose-derived mesenchymal stromal cells (AD-MSCs) have been extensively studied in
recent years. Their attractiveness is due to the ease of obtaining clinical material (fat tissue …
recent years. Their attractiveness is due to the ease of obtaining clinical material (fat tissue …