Single-molecule localization microscopy

M Lelek, MT Gyparaki, G Beliu, F Schueder… - Nature reviews …, 2021 - nature.com
Single-molecule localization microscopy (SMLM) describes a family of powerful imaging
techniques that dramatically improve spatial resolution over standard, diffraction-limited …

Xanthene, cyanine, oxazine and BODIPY: the four pillars of the fluorophore empire for super-resolution bioimaging

S Samanta, K Lai, F Wu, Y Liu, S Cai, X Yang… - Chemical Society …, 2023 - pubs.rsc.org
In the realm of biological research, the invention of super-resolution microscopy (SRM) has
enabled the visualization of ultrafine sub-cellular structures and their functions in live cells at …

Evaluation and development of deep neural networks for image super-resolution in optical microscopy

C Qiao, D Li, Y Guo, C Liu, T Jiang, Q Dai, D Li - Nature methods, 2021 - nature.com
Deep neural networks have enabled astonishing transformations from low-resolution (LR) to
super-resolved images. However, whether, and under what imaging conditions, such deep …

Super-resolution microscopy demystified

L Schermelleh, A Ferrand, T Huser, C Eggeling… - Nature cell …, 2019 - nature.com
Super-resolution microscopy (SRM) bypasses the diffraction limit, a physical barrier that
restricts the optical resolution to roughly 250 nm and was previously thought to be …

Visualizing and discovering cellular structures with super-resolution microscopy

YM Sigal, R Zhou, X Zhuang - Science, 2018 - science.org
Super-resolution microscopy has overcome a long-held resolution barrier—the diffraction
limit—in light microscopy and enabled visualization of previously invisible molecular details …

Fluorescence nanoscopy in cell biology

SJ Sahl, SW Hell, S Jakobs - Nature reviews Molecular cell biology, 2017 - nature.com
Fluorescence nanoscopy uniquely combines minimally invasive optical access to the
internal nanoscale structure and dynamics of cells and tissues with molecular detection …

Small-molecule fluorescent probes for live-cell super-resolution microscopy

L Wang, MS Frei, A Salim… - Journal of the American …, 2018 - ACS Publications
Super-resolution fluorescence microscopy is a powerful tool to visualize biomolecules and
cellular structures at the nanometer scale. Employing these techniques in living cells has …

Small-molecule fluorogenic probes for mitochondrial nanoscale imaging

R Zhai, B Fang, Y Lai, B Peng, H Bai, X Liu… - Chemical Society …, 2023 - pubs.rsc.org
Mitochondria are inextricably linked to the development of diseases and cell metabolism
disorders. Super-resolution imaging (SRI) is crucial in enhancing our understanding of …

Fast, long-term, super-resolution imaging with Hessian structured illumination microscopy

X Huang, J Fan, L Li, H Liu, R Wu, Y Wu, L Wei… - Nature …, 2018 - nature.com
To increase the temporal resolution and maximal imaging time of super-resolution (SR)
microscopy, we have developed a deconvolution algorithm for structured illumination …

Single particle tracking: from theory to biophysical applications

H Shen, LJ Tauzin, R Baiyasi, W Wang… - Chemical …, 2017 - ACS Publications
After three decades of developments, single particle tracking (SPT) has become a powerful
tool to interrogate dynamics in a range of materials including live cells and novel catalytic …