Recent trends in praziquantel nanoformulations for helminthiasis treatment
AC Mengarda, B Iles, JP F. Longo… - Expert Opinion on Drug …, 2022 - Taylor & Francis
Introduction Infections caused by parasitic flatworms impose a considerable worldwide
health burden. Recently, World Health Organization launched its roadmap for neglected …
health burden. Recently, World Health Organization launched its roadmap for neglected …
Drug repurposing: considerations to surpass while re-directing old compounds for new treatments
D Juárez-López, A Schcolnik-Cabrera - Archives of Medical Research, 2021 - Elsevier
Drug repurposing has increased in recent years as an attractive option for treating a number
of diseases. Compared to those brought forward via traditional chemical development, drugs …
of diseases. Compared to those brought forward via traditional chemical development, drugs …
[HTML][HTML] Therapeutic efficacy of carvacrol-loaded nanoemulsion in a mouse model of schistosomiasis
ES Xavier, RL de Souza, VC Rodrigues… - Frontiers in …, 2022 - frontiersin.org
Since praziquantel is the only drug available to treat schistosomiasis, a neglected parasitic
disease that affects more than 240 million people worldwide, there is an urgent demand for …
disease that affects more than 240 million people worldwide, there is an urgent demand for …
Brazilian red propolis exhibits antiparasitic properties in vitro and reduces worm burden and egg production in an mouse model harboring either early or chronic …
MP Silva, TM Silva, AC Mengarda, MC Salvadori… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Propolis has been used in folk medicine for thousands of
years and, in the past few decades, it has attracted renewed interest. Although propolis has …
years and, in the past few decades, it has attracted renewed interest. Although propolis has …
[HTML][HTML] Susceptibility of Angiostrongylus cantonensis larvae to anthelmintic drugs
DB Roquini, GL Silva, LLG Ferreira… - Frontiers in …, 2022 - frontiersin.org
Human helminthiasis affects approximately one in five people in the world and
disproportionally affects the poorest and most deprived communities. Human …
disproportionally affects the poorest and most deprived communities. Human …
Antiparasitic activity of piplartine (piperlongumine) in a mouse model of schistosomiasis
Schistosomiasis is one of the most important parasitic infections in terms of its negative
effects on public health and economics. Since praziquantel is currently the only drug …
effects on public health and economics. Since praziquantel is currently the only drug …
Licarin A, a neolignan isolated from Nectandra oppositifolia Nees & Mart. (Lauraceae), exhibited moderate preclinical efficacy against Schistosoma mansoni …
AC Mengarda, MP Silva, ME Cirino… - Phytotherapy …, 2021 - Wiley Online Library
Schistosomiasis is a widespread human parasitic disease currently affecting over 200
million people, particularly in poor communities. Chemotherapy for schistosomiasis relies …
million people, particularly in poor communities. Chemotherapy for schistosomiasis relies …
[HTML][HTML] Neolignans isolated from Saururus cernuus L. (Saururaceae) exhibit efficacy against Schistosoma mansoni
JR Brito, P Wilairatana, DB Roquini, BC Parra… - Scientific Reports, 2022 - nature.com
Schistosomiasis, a parasitic disease caused by the blood fluke of the genus Schistosoma,
affects over 230 million people, especially in developing countries. Despite the significant …
affects over 230 million people, especially in developing countries. Despite the significant …
15β-Senecioyl-oxy-ent-kaur-16-en-19-oic Acid, a Diterpene Isolated from Baccharis lateralis, as Promising Oral Compound for the Treatment of Schistosomiasis
DP Sessa, AC Mengarda, PE Simplicio… - Journal of Natural …, 2020 - ACS Publications
Praziquantel is the only available drug to treat schistosomiasis, and therefore, urgent studies
must be performed to identify new anthelmintic agents. This study reports the anthelmintic …
must be performed to identify new anthelmintic agents. This study reports the anthelmintic …
[HTML][HTML] Pyrazoline derivatives as promising novel antischistosomal agents
CS Morais, AC Mengarda, FB Miguel, KB Enes… - Scientific Reports, 2021 - nature.com
Praziquantel is the only available drug to treat schistosomiasis, a parasitic disease that
currently infects more than 240 million people globally. Due to increasing concerns about …
currently infects more than 240 million people globally. Due to increasing concerns about …