The introduction of in vitro nucleic acid amplification techniques, led by real-time PCR, into
the clinical microbiology laboratory has transformed the laboratory detection of viruses and …

We have developed a flexible, accurate and highly multiplexed SNP genotyping assay for
high-throughput genetic analysis of large populations on a bead array platform. The novel …

Hepatocellular carcinoma (HCC) is a highly heterogeneous disease, and prior attempts to
develop genomic-based classification for HCC have yielded highly divergent results …

Physical interactions between genetic elements located throughout the genome play
important roles in gene regulation and can be identified with the Chromosome Conformation …

Background It is a challenge to identify patients who, after undergoing potentially curative
treatment for hepatocellular carcinoma, are at greatest risk for recurrence. Such high-risk …

Inhibitors of the ALK and EGF receptor tyrosine kinases provoke dramatic but short-lived
responses in lung cancers harboring EML4-ALK translocations or activating mutations of …

Lowland rice roots have a unique physiological response to drought because of their
adaptation to flooded soil. Rice root attributes that facilitate growth under flooded conditions …

Abstract Background Triple Negative subset of (TN) Breast Cancers (BC), a close associate
of the basal-like subtype (with limited discordance) is an aggressive form of the disease …

The transcription factor EGR1 is a tumor suppressor gene that is downregulated in many
cancer types. Clinically, loss of EGR1 translates to increased tumor transformation and …

Predicting drug response in cancer patients remains a major challenge in the clinic. We
have perfected an ex vivo, reproducible, rapid and personalized culture method to …