Importance Prostate cancer is the second leading cause of cancer death among US men.
Objective To systematically review evidence on prostate-specific antigen (PSA)–based …

Background: Screening can detect prostate cancer at earlier, asymptomatic stages, when
treatments might be more effective. Purpose: To update the 2002 and 2008 US Preventive …

Background The effect of screening with prostate-specific–antigen (PSA) testing and digital
rectal examination on the rate of death from prostate cancer is unknown. This is the first …

Background—Frailty is an emerging concept in medicine yet to be explored as a risk factor
in cardiac surgery. Where elderly patients are increasingly referred for cardiac surgery, the …

Context Prostate cancer is the most frequent male cancer. Since the median age of
diagnosis is 66 yr, many patients require both geriatric and urologic evaluation if treatment is …

Methods The Canadian Task Force on Preventive Health Care is an independent panel of
volunteer clinicians and methodologists that makes recommendations about clinical …

Purpose Older men are more likely to be diagnosed with high-risk prostate cancer and to
have lower overall survival. As a result, age often plays a role in treatment choice. However …

Summary In 2010, the International Society of Geriatric Oncology (SIOG) developed
treatment guidelines for men with prostate cancer who are older than 70 years old. In 2013 …

We sought to test whether frailty may be predictive of operative risk in older adults with
medical problems. One hundred and twenty-five patients at least 70 years of age had a …

Prostate cancer is the most frequently diagnosed malignancy in American men, and a more
aggressive form of the disease is particularly prevalent among African Americans. The …