Roles of chitinase 3-like 1 in the development of cancer, neurodegenerative diseases, and inflammatory diseases

IJ Yeo, CK Lee, SB Han, J Yun, JT Hong - Pharmacology & therapeutics, 2019 - Elsevier
Abstract Chitinase 3-like 1 (CHI3L1) is a secreted glycoprotein that mediates inflammation,
macrophage polarization, apoptosis, and carcinogenesis. The expression of CHI3L1 is …

Chitinase 3 like-1: an emerging molecule involved in diabetes and diabetic complications

M Di Rosa, L Malaguarnera - Pathobiology, 2016 - karger.com
Abstract Chitinase 3 like-1 (CHI3L1) is a chitinase-like protein member of family 18
chitinases, expressed in innate immune cells and involved in endothelial dysfunction and …

Flavanol Consumption in Healthy Men Preserves Integrity of Immunological‐Endothelial Barrier Cell Functions: Nutri (epi) genomic Analysis

D Milenkovic, A Rodriguez‐Mateos… - Molecular nutrition & …, 2022 - Wiley Online Library
Scope While cocoa flavanol (CF) consumption improves cardiovascular risk biomarkers,
molecular mechanisms underlying their protective effects are not understood. Objective To …

Neuroinflammation and tau interact with amyloid in predicting sleep problems in aging independently of atrophy

AM Fjell, AV Idland, R Sala-Llonch, LO Watne… - Cerebral …, 2018 - academic.oup.com
Sleep problems relate to brain changes in aging and disease, but the mechanisms are
unknown. Studies suggest a relationship between β-amyloid (Aβ) accumulation and sleep …

[HTML][HTML] Atherosclerosis is exacerbated by chitinase-3-like-1 in amyloid precursor protein transgenic mice

YY Jung, KC Kim, MH Park, Y Seo, H Park, MH Park… - Theranostics, 2018 - ncbi.nlm.nih.gov
Although the important role of amyloid precursor protein (APP) in vascular diseases
associated with Alzheimer's disease (AD) has been demonstrated, the underlying molecular …

Chitinase-3-like 1 is a biomarker of acute kidney injury and mortality in paediatric severe malaria

AL Conroy, MT Hawkes, R Elphinstone, RO Opoka… - Malaria journal, 2018 - Springer
Abstract Background Chitinase-3-like 1 (CHI3L1) is a glycoprotein elevated in paediatric
severe malaria, and an emerging urinary biomarker of acute kidney injury (AKI). Based on …

[PDF][PDF] Serum YKL-40/chitinase 3-like protein 1 level is an independent predictor of atherosclerosis development in patients with obstructive sleep apnoea syndrome.

EM Bakırcı, E Ünver, H Değirmenci… - Türk Kardiyoloji …, 2015 - jag.journalagent.com
METHODS We enrolled 40 consecutive patients newly diagnosed with OSAS by
polysomnography and 40 age-sex-and body mass index-matched controls. Exclusion …

Plasm YKL‐40 levels are associated with hypertension in patients with obstructive sleep apnea

K Li, Z Chen, Y Qin, YX Wei - BioMed Research International, 2019 - Wiley Online Library
Background. Obstructive sleep apnea (OSA) is a common disease. It can cause many
serious complications. OSA may increase the risk of hypertension. However, the exact …

YKL-40 serum levels are predicted by inflammatory state, age and diagnosis of idiopathic inflammatory myopathies

M Vázquez-Del Mercado, F Pérez-Vázquez… - Scientific Reports, 2023 - nature.com
YKL-40 increase according to the aging process, and its functions have been associated
with tissue remodeling and systemic inflammation. In Rheumatoid Arthritis (RA) it has been …

[PDF][PDF] Plasma YKL-40 levels correlate with the severity of coronary atherosclerosis assessed with the SYNTAX score

K Sciborski, W Kuliczkowski, B Karolko… - Pol Arch Intern …, 2018 - academia.edu
Plasma YKL ‑40 levels correlate with the severity of coronary atherosclerosis assessed with
the SYNTAX score Page 1 POLISH ARCHIVES OF INTERNAL MEDICINE 2018; 128 (11) …