The effectiveness of anticancer drugs in treating a solid tumour is dependent on delivery of
the drug to virtually all cancer cells in the tumour. The distribution of drug in tumour tissue …

Since its license in 1978, cisplatin has proved to be one of the most successful
chemotherapeutic agents in the world. However, two acute challenges facing cisplatin …

Forty years after the first reports on stimuli-responsive phase transitions in synthetic
hydrogels, the first medicines based on responsive components are approaching the …

Thermosensitive liposomes have been put forward as a strategy to improve upon the limited
tumor drug availability associated with conventional non-thermosensitive liposomes …

Hyperthermia has demonstrated clinical success in improving the efficacy of both chemo-
and radio-therapy in solid tumors. Pre-clinical and clinical research studies have …

In this Review, we attempt to offer a thorough description of all of the chemical components
and the rationale behind the design of temperature-sensitive vesicle systems, as well as the …

Progress in nanotechnology has enabled us to open many new fronts in biomedical
research by exploiting the peculiar properties of materials at the nanoscale. The thermal …

Currently, we are facing increasing demand to develop efficient systems for the detection
and treatment of diseases that can realistically improve distinct aspects of healthcare in our …

Triggered drug delivery strategies have been shown to enhance drug accumulation at target
diseased sites in comparison to administration of free drug. In particular, many studies have …

An amphiphilic copolymer, folic acid (FA) modified poly (ethylene glycol)-poly (lactic-co-
glycolic acid)(FA-PEG-PLGA) was prepared and explored as a nanometer carrier for the co …