Abstract The translocator protein (18 kDa)(TSPO) is localized primarily in the outer
mitochondrial membrane of steroid-synthesizing cells, including those in the central and …

The corpus luteum (CL) is one of the few endocrine glands that forms from the remains of
another organ and whose function and survival are limited in scope and time. The CL is the …

Mitochondria play a central role in energy metabolism within the cell. Mitochondrial
dysfunctions lead to various neurodegenerative disorders and to the so-called …

The transfer of cholesterol from the outer to the inner mitochondrial membrane is the rate-
limiting step in hormone-induced steroid formation. To ensure that this step is achieved …

Steroid hormones are critical for organismal development and health. The rate-limiting step
in steroidogenesis is the transport of cholesterol from the outer mitochondrial membrane …

Cholesterol transport from the outer to the inner mitochondrial membrane is the rate-
determining step in steroid and bile acid biosyntheses. Biochemical, pharmacological and …

Adrenal gonadal, placental and brain mitochondria contain several steroidogenic enzymes,
notably the cholesterol side chain cleavage enzyme, P450scc, which is the enzymatic rate …

Exercise has beneficial effects on brain function, including the promotion of plasticity and the
enhancement of learning and memory performance. Previously we found that exercise …

Neurosteroids are synthetized in the central and the peripheral nervous system, in glial cells,
and also in neurons, from cholesterol or sieroidal precursors imported from peripheral …

All animal subcellular membranes require cholesterol, which influences membrane fluidity
and permeability, fission and fusion processes, and membrane protein function. The …