Fish T cells: recent advances through genomics

KJ Laing, JD Hansen - Developmental & Comparative Immunology, 2011 - Elsevier
This brief review is intended to provide a concise overview of the current literature
concerning T cells, advances in identifying distinct T cell functional subsets, and in …

Overview of the fish adaptive immune system

CJ Secombes, R Belmonte - Fish vaccines, 2016 - Springer
This chapter describes the immune responses that are elicited by vaccination of fish and that
are key to providing protection against future encounter with these same pathogens. The …

Diversity of teleost leukocyte molecules: Role of alternative splicing

K Maisey, M Imarai - Fish & Shellfish Immunology, 2011 - Elsevier
Alternative splicing is an important mechanism of gene expression control that also
produces a large proteome from a limited number of genes. In the immune system of …

Single-nuclei transcriptome analysis of channel catfish spleen provides insight into the immunome of an aquaculture-relevant species

JE Aldersey, MD Lange, BH Beck, JW Abernathy - Plos one, 2024 - journals.plos.org
The catfish industry is the largest sector of US aquaculture production. Given its role in food
production, the catfish immune response to industry-relevant pathogens has been …

Splenic γδ T cell subsets can be separated by a novel mab specific for two CD45 isoforms

D Huhle, S Hirmer, TW Göbel - Developmental & comparative immunology, 2017 - Elsevier
CD45 isoforms have been identified in a variety of different species and mab against various
isoforms have been instrumental to define cellular subsets. In the process of generating …

Grouper (Epinephelus coioides) TCR signaling pathway was involved in response against Cryptocaryon irritans infection

ZX Li, YW Li, S Xu, Y Xu, ZQ Mo, XM Dan… - Fish & shellfish …, 2017 - Elsevier
T cell activation is a complicated process accompanying with the activation of T cell receptor
(TCR) signaling pathway, which is not well described in teleost fish. The initiation of this …

Identification of goldfish (Carassius auratus L.) leukocyte immune-type receptors shows alternative splicing as a potential mechanism for receptor diversification

J Wang, M Belosevic, JL Stafford - Molecular Immunology, 2020 - Elsevier
Leukocyte immune-type receptors (LITRs) are a multigene family of teleost
immunoregulatory proteins that share structural, phylogenetic, and likely functional …

A monoclonal antibody for the CD45 receptor in the teleost fish Dicentrarchus labrax

C Marozzi, F Bertoni, E Randelli, F Buonocore… - Developmental & …, 2012 - Elsevier
The CD45 tyrosine phosphatase plays an important role in regulating T lymphocyte
activation in vertebrate species. In this study we describe some molecular and functional …

[HTML][HTML] A spontaneous deletion within the desmoglein 3 extracellular domain of mice results in hypomorphic protein expression, immunodeficiency, and a wasting …

EI Kountikov, JC Poe, NJ Maclver, JC Rathmell… - The American Journal of …, 2015 - Elsevier
Desmoglein 3 is a transmembrane component of desmosome complexes that mediate
epidermal cell-to-cell adhesion and tissue integrity. Antibody blockade of desmoglein 3 …

Identification and functional characterization of a subset of goldfish (Carassius auratus) leukocyte immune-type receptors (CaLITRs) expressed by myeloid cell-types

J Wang - 2024 - era.library.ualberta.ca
Originally discovered in the channel catfish, Ictalurus punctatus leukocyte immune-type
receptors (IpLITRs) are members of the immunoglobulin superfamily (IgSF) and several of …