Atherosclerosis is a progressive disease in which endothelial cell dysfunction, macrophage
foam cell formation, and smooth muscle cell migration and proliferation, lead to the loss of …

Non-alcoholic fatty liver disease affects 20–40% of the population. Its active form, non-
alcoholic steatohepatitis (NASH), is characterised by hepatocyte injury, liver inflammation …

Hepatocellular carcinoma (HCC) is an immunotherapy-resistant malignancy characterized
by high cellular heterogeneity. The diversity of cell types and the interplay between tumor …

MicroRNAs (miRNAs) are a class of noncoding RNAs that regulate target gene expression
at the posttranscriptional level. Here, we report that secreted miRNAs can serve as signaling …

Cardiometabolic diseases are one of the leading causes for disability and mortality in the
Western world. The prevalence of these chronic diseases is expected to rise even further in …

Levels of obesity have reached epidemic proportions on a global scale, which has led to
considerable increases in health problems and increased risk of several diseases, including …

Background Hyperlipidemia-induced apoptosis mediated by fatty acid translocase CD36 is
associated with increased uptake of ox-LDL or fatty acid in macrophages, hepatocytes and …

Non-alcoholic fatty liver disease (NAFLD) is an increasingly important cause of chronic liver
disease globally. Similar to metabolic syndrome and obesity, NAFLD is associated with …

Membrane CD36 functions in the uptake of fatty acids (FAs), oxidized lipoproteins and in
signal transduction after binding these ligands. In rodents, CD36 is implicated in abnormal …

Abstract Ethnopharmacological relevance Ginsenoside Rg1 (Rg1) is one of the main active
components in Panax ginseng CA Meyer (ginseng), which has been widely used to delay …