Inflammation in Development and Aging: Insights from the Zebrafish Model
M Mastrogiovanni, FJ Martínez-Navarro… - International Journal of …, 2024 - mdpi.com
Zebrafish are an emergent animal model to study human diseases due to their significant
genetic similarity to humans, swift development, and genetic manipulability. Their utility …
genetic similarity to humans, swift development, and genetic manipulability. Their utility …
p65 signaling dynamics drive the developmental progression of hematopoietic stem and progenitor cells through cell cycle regulation
Most gene functions have been discovered through phenotypic observations under loss of
function experiments that lack temporal control. However, cell signaling relies on limited …
function experiments that lack temporal control. However, cell signaling relies on limited …
Blood and guts: how the intestinal microbiome shapes hematopoiesis and treatment of hematologic disease
J Fernandez Sanchez, AA Maknojia, KY King - Blood, 2024 - ashpublications.org
Over the past 10 years, there has been a marked increase in recognition of the interplay
between the intestinal microbiome and the hematopoietic system. Despite their apparent …
between the intestinal microbiome and the hematopoietic system. Despite their apparent …
Tropomyosin 1 deficiency facilitates cell state transitions and enhances hemogenic endothelial cell specification during hematopoiesis
MB Wilken, G Fonar, R Qiu, L Bennett, J Tober… - Stem Cell Reports, 2024 - cell.com
Tropomyosins coat actin filaments to impact actin-related signaling and cell morphogenesis.
Genome-wide association studies have linked Tropomyosin 1 (TPM1) with human blood trait …
Genome-wide association studies have linked Tropomyosin 1 (TPM1) with human blood trait …
[HTML][HTML] Integrated local and systemic communication factors regulate nascent hematopoietic progenitor escape during developmental hematopoiesis
C Shalaby, J Garifallou, CS Thom - International Journal of Molecular …, 2024 - mdpi.com
Mammalian blood cells originate from specialized 'hemogenic'endothelial (HE) cells in
major arteries. During the endothelial-to-hematopoietic transition (EHT), nascent …
major arteries. During the endothelial-to-hematopoietic transition (EHT), nascent …
Insect hormone PTTH regulates lifespan through temporal and spatial activation of NF-κB signaling during metamorphosis
P Kang, P Liu, J Kim, A Kumar, M Bolton, W Murzyna… - …, 2024 - pmc.ncbi.nlm.nih.gov
The prothoracicotropic hormone (PTTH) is a well-known neuropeptide that regulates insect
metamorphosis (the juvenile-to-adult transition) by inducing the biosynthesis of steroid …
metamorphosis (the juvenile-to-adult transition) by inducing the biosynthesis of steroid …
The role of nfkb1 in hemogenic endothelial cell production
G Dubansky - 2023 - search.proquest.com
Blood related disorders like acute myelogenous leukemia often rely on allogeneic
hematopoietic stem cell transplantations as a form of therapy. However, graft-versus-host …
hematopoietic stem cell transplantations as a form of therapy. However, graft-versus-host …