Leg disorders in broiler chickens: a review of current knowledge

K Liu, Y He, B Xu, L Lin, P Chen, MK Iqbal… - Animal …, 2023 - Taylor & Francis
Ensuring improved leg health is an important prerequisite for broilers to achieve optimal
production performance and welfare status. Broiler leg disease is characterized by leg …

Cellular, molecular and genetical overview of avian tibial dyschondroplasia

AR Jahejo, WX Tian - Research in Veterinary Science, 2021 - Elsevier
Tibial dyschondroplasia (TD) is an intractable avian bone disease that causes severe
poultry economic losses. The pathogenicity of TD is unknown. Therefore, TD disease has …

Effect of tetramethyl thiuram disulfide (thiram) in relation to tibial dyschondroplasia in chickens

H Zhang, K Mehmood, X Jiang, W Yao, M Iqbal… - … Science and Pollution …, 2018 - Springer
Tetramethyl thiuram disulfide (thiram) is one of the important pesticides, which is extensively
used in agriculture, but if it is combined with the cell membrane, then it causes membrane …

A network pharmacology approach to explore active compounds and pharmacological mechanisms of epimedium for treatment of premature ovarian insufficiency

H Zhao, Y Shan, Z Ma, M Yu, B Gong - Drug Design, Development …, 2019 - Taylor & Francis
Background and purpose Premature ovarian insufficiency (POI) refers to a
hypergonadotropic hypoestrogenism and the condition of pre-onset ovarian function failure …

Effect of Total Flavonoids of Rhizoma drynariae on Tibial Dyschondroplasia by Regulating BMP-2 and Runx2 Expression in Chickens

W Yao, H Zhang, X Jiang, K Mehmood… - Frontiers in …, 2018 - frontiersin.org
Tibial dyschondroplasia (TD) is an abnormality of the growth cartilage that occurs in
chickens and other rapidly growing avian species. This disease not only cause huge …

Residue of thiram in food, suppresses immune system stress signals and disturbs sphingolipid metabolism in chickens

Y Liu, J Yi, Y Li, R Hussain, S Zhu, Y Li… - Veterinary Immunology …, 2022 - Elsevier
Thiram, a well-known sulfur containing organic compound is frequently and extensively
used in agriculture because of high biological activity to control different pests. In certain …

[HTML][HTML] Sodium butyrate ameliorates thiram-induced tibial dyschondroplasia and gut microbial dysbiosis in broiler chickens

Y Zhang, Y Ding, Q Mo, MFA Kulyar, Y He… - Ecotoxicology and …, 2022 - Elsevier
Thiram is a dithiocarbamate pesticide widely used in agriculture as a fungicide for storing
grains to prevent fungal diseases. However, its residues have threatened the safety of …

[HTML][HTML] Cluster of differentiation 147 (CD147) expression is linked with thiram induced chondrocyte's apoptosis via Bcl-2/Bax/Caspase-3 signalling in tibial growth …

MFA Kulyar, W Yao, Y Ding, H Du, K Li, L Zhang… - Ecotoxicology and …, 2021 - Elsevier
Tibial dyschondroplasia (TD) is a metabolic disease of young poultry that affects bone
andcartilage's growth. It mostly occurs in broilers due to thiram toxicity in the feed. In this …

[HTML][HTML] Comprehensive analysis of differently expression mRNA and non-coding RNAs, and their regulatory mechanisms on relationship in thiram-induced tibial …

Y Lu, H Xu, Y Jiang, Z Hu, R Du, X Zhao, Y Tian… - Ecotoxicology and …, 2022 - Elsevier
Thiram pollution is one of the main causes of tibial dyschondroplasia (TD) induced by feed
sources. Several studies have speculated that miRNA, circRNA and lncRNA may have …

Total Flavonoids of Rhizoma Drynariae Ameliorate Bone Growth in Experimentally Induced Tibial Dyschondroplasia in Chickens via Regulation of OPG/RANKL Axis

T Xu, J Zheng, WX Jin, L Li, L Lin, A Shaukat… - Frontiers in …, 2022 - frontiersin.org
Background: Rhizoma Drynariae, traditional Chinese herb, is widely used to treat and
prevent bone disorders. However, experimental evidence on the use of Rhizoma Drynariae …