Obesity and diabetes now considered global epidemics. The prevalence rates of diabetes
are increasing in parallel with the rates of obesity and the strong connection between these …

The burden of cardiovascular and metabolic diseases worldwide is staggering. The
emergence of systems approaches in biology promises new therapies, faster and cheaper …

Vertebrate glycans constitute a large, important, and dynamic set of post‐translational
modifications that are notoriously difficult to manipulate and image. Although the chemical …

Aquaculture has become an agronomic activity with noticeable development around the
world to respond to the simultaneous decrease of fish captures and the increasing demand …

Cytokines represent essential mediators of cell–cell communication with particularly
important roles within the immune system. These secreted factors are produced in response …

To unravel the evolutionarily conserved genetic network underlying energy homeostasis, we
performed a systematic in vivo gene knockdown screen in Drosophila. We used a transgenic …

Zebrafish (Danio rerio) have become popular as model organism in research. Many strains
are readily available, which not only differ morphologically, but also genetically …

Summary 1α, 25 (OH) 2 D 3 (vitamin D 3) is crucial for mineral homeostasis in mammals, but
the precise effects of 1α, 25 (OH) 2 D 3 in adipose tissue remain to be clarified in vivo. The …

Fat distribution is an independent cardiometabolic risk factor. However, its molecular and
cellular underpinnings remain obscure. Here we demonstrate that two independent GWAS …

Zebrafish are an ideal model organism to study lipid metabolism and to elucidate the
molecular underpinnings of human lipid-associated disorders. Unlike murine models, to …