Cancer cell plasticity during tumor progression, metastasis and response to therapy
A Pérez-González, K Bévant, C Blanpain - Nature cancer, 2023 - nature.com
Cell plasticity represents the ability of cells to be reprogrammed and to change their fate and
identity, enabling homeostasis restoration and tissue regeneration following damage. Cell …
identity, enabling homeostasis restoration and tissue regeneration following damage. Cell …
Innovative treatment strategies to accelerate wound healing: trajectory and recent advancements
P Kolimi, S Narala, D Nyavanandi, AAA Youssef… - Cells, 2022 - mdpi.com
Wound healing is highly specialized dynamic multiple phase process for the repair of
damaged/injured tissues through an intricate mechanism. Any failure in the normal wound …
damaged/injured tissues through an intricate mechanism. Any failure in the normal wound …
Linking EMT programmes to normal and neoplastic epithelial stem cells
AW Lambert, RA Weinberg - Nature Reviews Cancer, 2021 - nature.com
Epithelial stem cells serve critical physiological functions in the generation, maintenance
and repair of diverse tissues through their ability to self-renew and spawn more specialized …
and repair of diverse tissues through their ability to self-renew and spawn more specialized …
[HTML][HTML] Wound healing: a cellular perspective
Wound healing is one of the most complex processes in the human body. It involves the
spatial and temporal synchronization of a variety of cell types with distinct roles in the …
spatial and temporal synchronization of a variety of cell types with distinct roles in the …
[HTML][HTML] Breast cancer development and progression: Risk factors, cancer stem cells, signaling pathways, genomics, and molecular pathogenesis
Y Feng, M Spezia, S Huang, C Yuan, Z Zeng, L Zhang… - Genes & diseases, 2018 - Elsevier
As the most commonly occurring cancer in women worldwide, breast cancer poses a
formidable public health challenge on a global scale. Breast cancer consists of a group of …
formidable public health challenge on a global scale. Breast cancer consists of a group of …
Cancer stem cells revisited
The cancer stem cell (CSC) concept was proposed four decades ago, and states that tumor
growth, analogous to the renewal of healthy tissues, is fueled by small numbers of dedicated …
growth, analogous to the renewal of healthy tissues, is fueled by small numbers of dedicated …
Advanced drug delivery systems and artificial skin grafts for skin wound healing
Cutaneous injuries, especially chronic wounds, burns, and skin wound infection, require
painstakingly long-term treatment with an immense financial burden to healthcare systems …
painstakingly long-term treatment with an immense financial burden to healthcare systems …
Regeneration of the entire human epidermis using transgenic stem cells
T Hirsch, T Rothoeft, N Teig, JW Bauer, G Pellegrini… - Nature, 2017 - nature.com
Junctional epidermolysis bullosa (JEB) is a severe and often lethal genetic disease caused
by mutations in genes encoding the basement membrane component laminin-332 …
by mutations in genes encoding the basement membrane component laminin-332 …
The extracellular matrix dictates regional competence for tumour initiation
N Bansaccal, P Vieugue, R Sarate, Y Song… - Nature, 2023 - nature.com
The skin epidermis is constantly renewed throughout life,. Disruption of the balance between
renewal and differentiation can lead to uncontrolled growth and tumour initiation. However …
renewal and differentiation can lead to uncontrolled growth and tumour initiation. However …
Re-epithelialization of adult skin wounds: Cellular mechanisms and therapeutic strategies
P Rousselle, F Braye, G Dayan - Advanced Drug Delivery Reviews, 2019 - Elsevier
Cutaneous wound healing in adult mammals is a complex multi-step process involving
overlapping stages of blood clot formation, inflammation, re-epithelialization, granulation …
overlapping stages of blood clot formation, inflammation, re-epithelialization, granulation …