Snake venoms in drug discovery: Valuable therapeutic tools for life saving

T Mohamed Abd El-Aziz, AG Soares, JD Stockand - Toxins, 2019 - mdpi.com
Animal venoms are used as defense mechanisms or to immobilize and digest prey. In fact,
venoms are complex mixtures of enzymatic and non-enzymatic components with specific …

From fangs to pharmacology: the future of snakebite envenoming therapy

AH Laustsen, M Engmark, C Milbo… - Current …, 2016 - ingentaconnect.com
The snake is the symbol of medicine due to its association with Asclepius, the Greek God of
medicine, and so with good reasons. More than 725 species of venomous snakes have …

Venoms of Micrurus coral snakes: Evolutionary trends in compositional patterns emerging from proteomic analyses

B Lomonte, P Rey-Suárez, J Fernández, M Sasa, D Pla… - Toxicon, 2016 - Elsevier
The application of proteomic tools to the study of snake venoms has led to an impressive
growth in the knowledge about their composition (venomics), immunogenicity …

Snake Venom PLA2, a Promising Target for Broad‐Spectrum Antivenom Drug Development

H Xiao, H Pan, K Liao, M Yang… - BioMed research …, 2017 - Wiley Online Library
Snakebite envenomation is a neglected global health problem, causing substantial mortality,
disability, and psychological morbidity, especially in rural tropical and subtropical zones …

Coralsnake venomics: analyses of venom gland transcriptomes and proteomes of six Brazilian taxa

SD Aird, NJ da Silva Jr, L Qiu, A Villar-Briones… - Toxins, 2017 - mdpi.com
Venom gland transcriptomes and proteomes of six Micrurus taxa (M. corallinus, M.
lemniscatus carvalhoi, M. lemniscatus lemniscatus, M. paraensis, M. spixii spixii, and M …

Unveiling the Venom Composition of the Colombian Coral Snakes Micrurus helleri, M. medemi, and M. sangilensis

A Rodríguez-Vargas, AM Franco-Vásquez… - Toxins, 2023 - mdpi.com
Little is known of the biochemical composition and functional features of the venoms of
poorly known Colombian coral snakes. Here, we provide a preliminary characterization of …

Ancient Diversification of Three-Finger Toxins in Micrurus Coral Snakes

D Dashevsky, BG Fry - Journal of Molecular Evolution, 2018 - Springer
Coral snakes, most notably the genus Micrurus, are the only terrestrial elapid snakes in the
Americas. Elapid venoms are generally known for their potent neurotoxicity which is usually …

Unveiling the elusive and exotic: Venomics of the Malayan blue coral snake (Calliophis bivirgata flaviceps)

CH Tan, SY Fung, MKK Yap, PK Leong, JL Liew… - Journal of …, 2016 - Elsevier
The venom proteome of the Malayan blue coral snake, Calliophis bivirgata flaviceps from
west Malaysia was investigated by 1D-SDS-PAGE and shotgun-LCMS/MS. A total of 23 …

Functional, proteomic and transcriptomic characterization of the venom from Micrurus browni browni: Identification of the first lethal multimeric neurotoxin in coral …

M Bénard-Valle, E Neri-Castro, MF Yañez-Mendoza… - Journal of …, 2020 - Elsevier
Proteomic characterization of Micrurus browni browni venom showed approximately 41
components belonging to 9 protein families, mainly phospholipases A 2 (PLA 2 s) and three …

A review of rattlesnake venoms

P Phan, A Deshwal, TA McMahon, M Slikas, E Andrews… - Toxins, 2023 - mdpi.com
Venom components are invaluable in biomedical research owing to their specificity and
potency. Many of these components exist in two genera of rattlesnakes, Crotalus and …