Co-evolution of immunity and seasonal influenza viruses
AX Han, SPJ de Jong, CA Russell - Nature Reviews Microbiology, 2023 - nature.com
Seasonal influenza viruses cause recurring global epidemics by continually evolving to
escape host immunity. The viral constraints and host immune responses that limit and drive …
escape host immunity. The viral constraints and host immune responses that limit and drive …
Leveraging vaccination-induced protective antibodies to define conserved epitopes on influenza N2 neuraminidase
There is growing appreciation for neuraminidase (NA) as an influenza vaccine target;
however, its antigenicity remains poorly characterized. In this study, we isolated three …
however, its antigenicity remains poorly characterized. In this study, we isolated three …
[HTML][HTML] Mutational fitness landscape of human influenza H3N2 neuraminidase
Influenza neuraminidase (NA) has received increasing attention as an effective vaccine
target. However, its mutational tolerance is not well characterized. Here, the fitness effects …
target. However, its mutational tolerance is not well characterized. Here, the fitness effects …
Phylogenetic identification of influenza virus candidates for seasonal vaccines
The seasonal influenza (flu) vaccine is designed to protect against those influenza viruses
predicted to circulate during the upcoming flu season, but identifying which viruses are likely …
predicted to circulate during the upcoming flu season, but identifying which viruses are likely …