Design of experiments in the optimization of nanoparticle-based drug delivery systems
Abstract Design of experiment (DoE) is a powerful statistical technique used for variable
screening and optimization. It is based on the simultaneous variation of multiple factors with …
screening and optimization. It is based on the simultaneous variation of multiple factors with …
[PDF][PDF] Past Decade Work Done On Cubosomes Using Factorial Design: A Fast Track Information for Researchers..(2021)
Y Shravani, HA Ahad, C Haranath… - Int. J. Life Sci … - pdfs.semanticscholar.org
The objective of this review is to explore the past work done on Cubosomes as drug delivery
systems by factorial design. Cubosomes are Nanoparticulate systems made of amphiphilic …
systems by factorial design. Cubosomes are Nanoparticulate systems made of amphiphilic …
Pazopanib-laden lipid based nanovesicular delivery with augmented oral bioavailability and therapeutic efficacy against non-small cell lung cancer
The present investigation deals with the pazopanib-loaded solid lipid nanoparticles (Pazo-
SLNs) and their in-vitro and in-vivo assessments. Quality by design approach employing the …
SLNs) and their in-vitro and in-vivo assessments. Quality by design approach employing the …
Development of solid lipid nanoparticle as carrier of pioglitazone for amplification of oral efficacy: formulation design optimization, in-vitro characterization and in-vivo …
Pioglitazone (PGL) is a hypoglycemic therapeutic agent used in the treatment of diabetes
(type 2). The present research work was designed to prepare and optimize PGL loaded solid …
(type 2). The present research work was designed to prepare and optimize PGL loaded solid …
Development of dapagliflozin solid lipid nanoparticles as a novel carrier for oral delivery: statistical design, optimization, in-vitro and in-vivo characterization, and …
Controlling hyperglycemia and avoiding glucose reabsorption are significant goals in type 2
diabetes treatments. Among the numerous modes of medication administration, the oral …
diabetes treatments. Among the numerous modes of medication administration, the oral …
An artificial neural network approach to predict the effects of formulation and process variables on prednisone release from a multipartite system
The impact of formulation and process variables on the in-vitro release of prednisone from a
multiple-unit pellet system was investigated. Box-Behnken Response Surface Methodology …
multiple-unit pellet system was investigated. Box-Behnken Response Surface Methodology …
Preparation, characterization and pharmacokinetics of tolfenamic acid-loaded solid lipid nanoparticles
W Xu, Z Deng, Y Xiang, D Zhu, D Yi, Y Mo, Y Liu, L Qin… - Pharmaceutics, 2022 - mdpi.com
The clinical use of nonsteroidal anti-inflammatory drugs is limited by their poor water
solubility, unstable absorption, and low bioavailability. Solid lipid nanoparticles (SLNs) …
solubility, unstable absorption, and low bioavailability. Solid lipid nanoparticles (SLNs) …
Assessment of the antidiabetic potentiality of glyburide loaded glyceryl monostearate solid lipid nanoparticles
S Mukherjee, S Maity, B Ghosh, T Chakraborty… - Journal of Drug Delivery …, 2020 - Elsevier
The high rate homogenisation techniques was used for preparing glyburide loaded glyceryl
monostearate solid lipid nanoparticles (Glb-SLNs) to improve the drug's solubility and oral …
monostearate solid lipid nanoparticles (Glb-SLNs) to improve the drug's solubility and oral …
[HTML][HTML] Preparation and evaluation of antidiabetic activity of mangiferin-loaded solid lipid nanoparticles
This study aimed to develop and optimize mangiferin-loaded solid lipid nanoparticles (MG-
SLNs) using the microemulsion technique and ultrasonication. The MG-SLNs were …
SLNs) using the microemulsion technique and ultrasonication. The MG-SLNs were …
Nanostructure-Based Drug Delivery in Alleviating Type 2 Diabetes Mellitus
Type 2 diabetes mellitus is a global health concern with an increasing rate of prevalence
and its impact on the patient's quality of life. Conventional treatment strategies aimed for …
and its impact on the patient's quality of life. Conventional treatment strategies aimed for …