Sepsis is the life-threatening organ dysfunction caused by a dysregulated host response to
infection and is the leading cause of death in intensive care units. Cardiac dysfunction …

There has been a significant evolution in the definition and management of sepsis over the
last three decades. This is driven in part due to the advances made in our understanding of …

Sepsis-induced cardiomyopathy (SICM) is common in septic patients with a high mortality
and is characterized by an abnormal immune response. Owing to cellular heterogeneity …

Objectives: To describe, with an emphasis on clinical applications, what is known about the
pathophysiology, management, and implications of septic cardiomyopathy in the adult ICU …

Sepsis is aggravated by an inappropriate immune response to invading microorganisms,
which occasionally leads to multiple organ failure. Several lines of evidence suggest that the …

Background Patients with sepsis-induced cardiomyopathy with cardiogenic shock have a
high mortality. This study assessed venoarterial extracorporeal membrane oxygenation (VA …

Background Sepsis is a common condition encountered by emergency and critical care
physicians, with significant costs, both economic and human. Myocardial dysfunction in …

The cardiovascular system plays a key role in sepsis, and septic myocardial depression is a
common finding associated with increased morbidity and mortality. Myocardial depression …

Aims Systolic dysfunction in septic shock is well recognized and, paradoxically, predicts
better outcome. In contrast, diastolic dysfunction is often ignored and its role in determining …

Septic shock, the most severe complication of sepsis, accounts for∼ 10% of all admissions
to intensive care. Our understanding of its complex pathophysiology remains incomplete but …