The contemporary management of peritoneal metastasis: A journey from the cold past of treatment futility to a warm present and a bright future

JM Foster, C Zhang, S Rehman… - CA: A Cancer …, 2023 - Wiley Online Library
Peritoneal metastasis (PM) is often regarded as a less frequent pattern of spread; however,
collectively across all spectra of primary tumors, the consequences of PM impact a large …

Advances in the management of peritoneal malignancies

V Kepenekian, A Bhatt, J Peron, M Alyami… - Nature Reviews …, 2022 - nature.com
Peritoneal surface malignancies (PSMs) are usually associated with a poor prognosis.
Nonetheless, in line with advances in the management of most abdominopelvic metastatic …

Cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy in patients with advanced ovarian cancer (OVHIPEC-1): final survival analysis of a …

SL Aronson, M Lopez-Yurda, SN Koole… - The Lancet …, 2023 - thelancet.com
Background The OVHIPEC-1 trial previously showed that the addition of hyperthermic
intraperitoneal chemotherapy (HIPEC) to interval cytoreductive surgery resulted in improved …

Hyperthermic intraperitoneal chemotherapy after interval cytoreductive surgery for patients with advanced-stage ovarian cancer who had received neoadjuvant …

JY Lee, YJ Lee, JH Son, S Kim, MC Choi, DH Suh… - JAMA …, 2023 - jamanetwork.com
Importance Hyperthermic intraperitoneal chemotherapy (HIPEC) followed by interval
cytoreductive surgery (ICS) has shown survival benefits for patients with advanced-stage …

Mechanistic insights on hyperthermic intraperitoneal chemotherapy in ovarian cancer

OG Huffman, DB Chau, AI Dinicu, R DeBernardo… - Cancers, 2023 - mdpi.com
Simple Summary Advanced ovarian cancer is the leading cause of gynecological death with
a high rate of reoccurrence indicating the critical need for improved therapeutics …

Hyperthermic Intraperitoneal Chemotherapy (HIPEC): New Approaches and Controversies on the Treatment of Advanced Epithelial Ovarian Cancer—Systematic …

L Della Corte, C Conte, M Palumbo, S Guerra… - Journal of Clinical …, 2023 - mdpi.com
Background: Hyperthermic intraperitoneal chemotherapy (HIPEC) after cytoreductive
surgery has been extensively studied in patients with peritoneal carcinomatosis, and it holds …

Adipocyte microenvironment in ovarian cancer: A critical contributor?

A Duarte Mendes, AR Freitas, R Vicente… - International Journal of …, 2023 - mdpi.com
Ovarian cancer is one of the most common gynecological malignancies and has low survival
rates. One of the main determinants of this unfavorable prognosis is the high rate of …

Neoadjuvant Chemotherapy plus Interval Cytoreductive Surgery with or without Hyperthermic Intraperitoneal Chemotherapy (NIHIPEC) in the Treatment of Advanced …

A Llueca, MV Ibañez, P Cascales, A Gil-Moreno… - Cancers, 2023 - mdpi.com
Simple Summary Advanced ovarian cancer (Stages III-IV) continues to be one of the
gynecological tumors with the highest mortality. Standard treatment consists of debulking …

Current research and development in hyperthermic intraperitoneal chemotherapy (HIPEC)—a cross-sectional analysis of clinical trials registered on ClinicalTrials. gov

K Ukegjini, M Guidi, K Lehmann, K Süveg, PM Putora… - Cancers, 2023 - mdpi.com
Simple Summary Peritoneal metastases have a poor prognosis, and one potential treatment
option is cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy …

HIPEC in Ovarian Cancer Is the Future… and Always Will Be? Results from a Spanish Multicentric Survey

A González Gil, Á Cerezuela Fernández-de Palencia… - Cancers, 2023 - mdpi.com
Simple Summary Treatment with intraperitoneal hyperthermic chemotherapy (HIPEC) has
been criticized in ovarian cancer due to the lack of prospective and randomized clinical trials …