[HTML][HTML] The female vaginal microbiome in health and bacterial vaginosis

X Chen, Y Lu, T Chen, R Li - Frontiers in cellular and infection …, 2021 - frontiersin.org
The vaginal microbiome is an intricate and dynamic microecosystem that constantly
undergoes fluctuations during the female menstrual cycle and the woman's entire life. A …

The role of gut and genital microbiota and the estrobolome in endometriosis, infertility and chronic pelvic pain

ME Salliss, LV Farland, ND Mahnert… - Human reproduction …, 2022 - academic.oup.com
BACKGROUND Endometriosis is a chronic, burdensome condition that is historically
understudied. Consequently, there is a lack of understanding of the etiology of the disease …

Bacterial vaginosis and health-associated bacteria modulate the immunometabolic landscape in 3D model of human cervix

P Łaniewski, MM Herbst-Kralovetz - npj Biofilms and Microbiomes, 2021 - nature.com
Bacterial vaginosis (BV) is an enigmatic polymicrobial condition characterized by a
depletion of health-associated Lactobacillus and an overgrowth of anaerobes. Importantly …

Bacterial vaginosis: current diagnostic avenues and future opportunities

MJ Redelinghuys, J Geldenhuys, H Jung… - Frontiers in cellular and …, 2020 - frontiersin.org
A healthy female genital tract harbors a microbiome dominated by lactic acid and hydrogen
peroxide producing bacteria, which provide protection against infections by maintaining a …

Interactions between microbiota and cervical epithelial, immune, and mucus barrier

M Dong, Y Dong, J Bai, H Li, X Ma, B Li… - Frontiers in cellular …, 2023 - frontiersin.org
The female reproductive tract harbours hundreds of bacterial species and produces
numerous metabolites. The uterine cervix is located between the upper and lower parts of …

Immunometabolic and potential tumor-promoting changes in 3D cervical cell models infected with bacterial vaginosis-associated bacteria

JD Maarsingh, P Łaniewski… - Communications …, 2022 - nature.com
Specific bacteria of the human microbiome influence carcinogenesis at diverse anatomical
sites. Bacterial vaginosis (BV) is the most common vaginal disorder in premenopausal …

Veillonellaceae family members uniquely alter the cervical metabolic microenvironment in a human three-dimensional epithelial model

ME Salliss, JD Maarsingh, C Garza… - npj Biofilms and …, 2021 - nature.com
Bacterial vaginosis (BV) is a gynecologic disorder characterized by a shift in cervicovaginal
microbiota from Lactobacillus spp. dominance to a polymicrobial biofilm composed of …

Members of Prevotella Genus Distinctively Modulate Innate Immune and Barrier Functions in a Human Three-Dimensional Endometrial Epithelial Cell Model

ZE Ilhan, P Łaniewski, A Tonachio… - The Journal of …, 2020 - academic.oup.com
Background Prevotella species are commonly isolated from the reproductive tract of women
with obstetric/gynecologic health complications. However, contributions of this genus to …

Commensal lactobacilli metabolically contribute to cervical epithelial homeostasis in a species-specific manner

NR Jimenez, JD Maarsingh, P Łaniewski… - MSphere, 2023 - Am Soc Microbiol
In reproductive-age women, the vaginal microbiome is typically dominated by one or a few
Lactobacillus species, including Lactobacillus crispatus, Lactobacillus iners, Lactobacillus …

Microbiome-mucosal immunity nexus: driving forces in respiratory disease progression

YC Park, SY Choi, Y Cha, HW Yoon, YM Son - Journal of Microbiology, 2024 - Springer
The importance of the complex interplay between the microbiome and mucosal immunity,
particularly within the respiratory tract, has gained significant attention due to its potential …