Resolution of inflammation: An organizing principle in biology and medicine
D Panigrahy, MM Gilligan, CN Serhan… - Pharmacology & …, 2021 - Elsevier
The resolution of inflammation has emerged as a critical endogenous process that protects
host tissues from prolonged or excessive inflammation that can become chronic. Failure of …
host tissues from prolonged or excessive inflammation that can become chronic. Failure of …
Corneal stromal repair and regeneration
The cornea is a specialized, transparent, avascular, immune-privileged, and heavily
innervated tissue that affords 2/3rd of refraction to the eye. Ocular injuries, infections, and …
innervated tissue that affords 2/3rd of refraction to the eye. Ocular injuries, infections, and …
Carcinogenesis: Failure of resolution of inflammation?
A Fishbein, BD Hammock, CN Serhan… - Pharmacology & …, 2021 - Elsevier
Inflammation in the tumor microenvironment is a hallmark of cancer and is recognized as a
key characteristic of carcinogens. However, the failure of resolution of inflammation in …
key characteristic of carcinogens. However, the failure of resolution of inflammation in …
Resolvins and protectins in inflammation resolution
CN Serhan, NA Petasis - Chemical reviews, 2011 - ACS Publications
The critical role of inflammatory processes in health and disease has long been recognized,
1 yet the detailed molecular mechanisms and biological events that regulate the progression …
1 yet the detailed molecular mechanisms and biological events that regulate the progression …
New pro-resolving n-3 mediators bridge resolution of infectious inflammation to tissue regeneration
While protective, the acute inflammatory response when uncontrolled can lead to further
tissue damage and chronic inflammation that is now widely recognized to play important …
tissue damage and chronic inflammation that is now widely recognized to play important …
[HTML][HTML] Anti-inflammatory agents: present and future
CA Dinarello - Cell, 2010 - cell.com
Inflammation involving the innate and adaptive immune systems is a normal response to
infection. However, when allowed to continue unchecked, inflammation may result in …
infection. However, when allowed to continue unchecked, inflammation may result in …
Discovery of specialized pro-resolving mediators marks the dawn of resolution physiology and pharmacology
CN Serhan - Molecular aspects of medicine, 2017 - Elsevier
It is with great pleasure that I write this foreword and introduction to this Special Issue
dedicated to the protective actions of the pro-resolving mediators and edited by my …
dedicated to the protective actions of the pro-resolving mediators and edited by my …
Specialized pro-resolving lipid mediators in the inflammatory response: An update
G Bannenberg, CN Serhan - … et Biophysica Acta (BBA)-Molecular and Cell …, 2010 - Elsevier
A new genus of specialized pro-resolving mediators (SPM) which include several families of
distinct local mediators (lipoxins, resolvins, protectins, and maresins) are actively involved in …
distinct local mediators (lipoxins, resolvins, protectins, and maresins) are actively involved in …
Resolution of acute inflammation and the role of resolvins in immunity, thrombosis, and vascular biology
BE Sansbury, M Spite - Circulation research, 2016 - Am Heart Assoc
Acute inflammation is a host-protective response that is mounted in response to tissue injury
and infection. Initiated and perpetuated by exogenous and endogenous mediators, acute …
and infection. Initiated and perpetuated by exogenous and endogenous mediators, acute …
Identification of chemerin receptor (ChemR23) in human endothelial cells: chemerin-induced endothelial angiogenesis
Chemerin acting via its distinct G protein-coupled receptor CMKLR1 (ChemR23), is a novel
adipokine, circulating levels of which are raised in inflammatory states. Chemerin shows …
adipokine, circulating levels of which are raised in inflammatory states. Chemerin shows …