Resolution of inflammation: An organizing principle in biology and medicine

D Panigrahy, MM Gilligan, CN Serhan… - Pharmacology & …, 2021 - Elsevier
The resolution of inflammation has emerged as a critical endogenous process that protects
host tissues from prolonged or excessive inflammation that can become chronic. Failure of …

Corneal stromal repair and regeneration

RR Mohan, D Kempuraj, S D'Souza, A Ghosh - Progress in retinal and eye …, 2022 - Elsevier
The cornea is a specialized, transparent, avascular, immune-privileged, and heavily
innervated tissue that affords 2/3rd of refraction to the eye. Ocular injuries, infections, and …

Carcinogenesis: Failure of resolution of inflammation?

A Fishbein, BD Hammock, CN Serhan… - Pharmacology & …, 2021 - Elsevier
Inflammation in the tumor microenvironment is a hallmark of cancer and is recognized as a
key characteristic of carcinogens. However, the failure of resolution of inflammation in …

Resolvins and protectins in inflammation resolution

CN Serhan, NA Petasis - Chemical reviews, 2011 - ACS Publications
The critical role of inflammatory processes in health and disease has long been recognized,
1 yet the detailed molecular mechanisms and biological events that regulate the progression …

New pro-resolving n-3 mediators bridge resolution of infectious inflammation to tissue regeneration

CN Serhan, N Chiang, J Dalli - Molecular aspects of medicine, 2018 - Elsevier
While protective, the acute inflammatory response when uncontrolled can lead to further
tissue damage and chronic inflammation that is now widely recognized to play important …

[HTML][HTML] Anti-inflammatory agents: present and future

CA Dinarello - Cell, 2010 - cell.com
Inflammation involving the innate and adaptive immune systems is a normal response to
infection. However, when allowed to continue unchecked, inflammation may result in …

Discovery of specialized pro-resolving mediators marks the dawn of resolution physiology and pharmacology

CN Serhan - Molecular aspects of medicine, 2017 - Elsevier
It is with great pleasure that I write this foreword and introduction to this Special Issue
dedicated to the protective actions of the pro-resolving mediators and edited by my …

Specialized pro-resolving lipid mediators in the inflammatory response: An update

G Bannenberg, CN Serhan - … et Biophysica Acta (BBA)-Molecular and Cell …, 2010 - Elsevier
A new genus of specialized pro-resolving mediators (SPM) which include several families of
distinct local mediators (lipoxins, resolvins, protectins, and maresins) are actively involved in …

Resolution of acute inflammation and the role of resolvins in immunity, thrombosis, and vascular biology

BE Sansbury, M Spite - Circulation research, 2016 - Am Heart Assoc
Acute inflammation is a host-protective response that is mounted in response to tissue injury
and infection. Initiated and perpetuated by exogenous and endogenous mediators, acute …

Identification of chemerin receptor (ChemR23) in human endothelial cells: chemerin-induced endothelial angiogenesis

J Kaur, R Adya, BK Tan, J Chen… - … and biophysical research …, 2010 - Elsevier
Chemerin acting via its distinct G protein-coupled receptor CMKLR1 (ChemR23), is a novel
adipokine, circulating levels of which are raised in inflammatory states. Chemerin shows …