The optical clarity of the cornea is essential for maintaining good visual acuity. Corneal
neovascularization, which is a major cause of vision loss worldwide, leads to corneal …

Inflammation and angiogenesis are frequently coupled in pathological situations such as
atherosclerosis, diabetes, and arthritis. The inflammatory response increases capillary …

Background The tumor microenvironment (TME) is a critical player in tumor progression,
metastasis and therapy outcomes. Tumor-associated macrophages (TAMs) are a well …

Angiogenesis is crucial for the success of most tissue engineering strategies. The natural
inflammatory response is a major regulator of vascularization, through the activity of different …

Adult skeletal muscle has a robust capacity for self-repair, owing to synergies between
muscle satellite cells and the immune system. In vitro models of muscle self-repair would …

The mechanisms by which macrophages control the inflammatory response, wound healing,
biomaterial-interactions, and tissue regeneration appear to be related to their activation …

Purpose Neovascular (wet) age-related macular degeneration (nAMD) is driven by VEGFs
A, C, and D, which promote angiogenesis and vascular permeability. Intravitreal injections of …

Corneal avascularity is necessary for the preservation of optimal vision. The cornea
maintains a dynamic balance between pro-and antiangiogenic factors that allows it to …

Vascular endothelial growth factors (VEGFs) are critical regulators of vascular and lymphatic
function during development, in health and in disease. There are five mammalian VEGF …

Historically, the eye has been considered as an organ free of lymphatic vessels. In recent
years, however, it became evident, that lymphatic vessels or lymphatic-like vessels …