OBJECTIVE: To review all available data and recommend a definition for polycystic ovary
syndrome (PCOS) based on published peer-reviewed data, whether already in use or not, to …

The adrenal gland is a source of sex steroid precursors, and its activity is particularly
relevant during fetal development and adrenarche. Following puberty, the synthesis of …

Objective To comprehensively characterize androgens and androgen precursors in classic
21-hydroxylase deficiency (21OHD) and to gain insights into the mechanisms of their …

Now in its Fifth Edition, the leading clinical reference on pediatric and adolescent
gynecology combines contemporary approaches to diagnosis with the latest medical and …

Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders
characterized by androgen excess, oligo-ovulation and polycystic ovaries. Although ovaries …

Abstract The 11-oxyandrogens, particularly 11-ketotestosterone, have been recognized as a
biologically important gonadal androgen in teleost (bony) fishes for decades, and their …

Abstract 11β-Hydroxyandrostenedione (11OHA4), a major C19 steroid produced by the
adrenal, was first reported in the 1950s. Initially the subject of numerous studies, interest …

Polycystic ovary syndrome (PCOS) affects about 4 to 6% of women of reproductive age and
accounts for at least 75% of hyperandrogenic patients. PCOS is diagnosed by the presence …

Adrenocortical secretion is up-regulated in women with polycystic ovary syndrome (PCOS),
and absolute adrenal androgen (AA) excess is evident in∼ 25% of these patients. We …

Adrenal steroidogenesis has, for decades, been depicted as three biosynthesis pathways–
the mineralocorticoid, glucocorticoid and androgen pathways with aldosterone, cortisol and …