The advent of the knowledge on human genetics, by the identification of disease-associated
variants, culminated in the understanding of human variability. With the genetic knowledge …

Aging is a highly complex molecular process, affecting nearly all tissue systems in humans
and is the highest risk factor in developing neurodegenerative disorders such as Alzheimer's …

Dendritic cells (DCs) are professional antigen-presenting cells (APCs) with the unique ability
to mediate inflammatory responses of the immune system. Given the critical role of DCs in …

GPCRs arguably represent the most effective current therapeutic targets for a plethora of
diseases. GPCRs also possess a pivotal role in the regulation of the physiological balance …

Breast cancer heterogeneity is evident at the clinical, histological and molecular level. High
throughput technologies allowed the identification of intrinsic subtypes that capture …

Boolean modelling of biological networks is a well-established technique for abstracting
dynamical biomolecular regulation in cells. Specifically, decoding linkages between salient …

MEDICINA DE PRECISIÓN: Page 1 EDITORIAL REV HISP CIENC SALUD 198 MEDICINA DE
PRECISIÓN: ¿UN NUEVO PARADIGMA EN SALUD? Hebel Urquia-Osorio 1, 2a, Issac Zablah …

Boolean networks are one of the models for studying complex dynamic behaviors in
biological systems. The analysis of attractors of these networks is very important. But the …

En los próximos años la medicina que practicamos pasará progresivamente de ser una
medicina reactiva, basada en la enfermedad, a una medicina personalizada, predictiva …