Structure and function of desmosomes
B Holthöfer, R Windoffer, S Troyanovsky… - International review of …, 2007 - Elsevier
Desmosomes are prominent adhesion sites that are tightly associated with the cytoplasmic
intermediate filament cytoskeleton providing mechanical stability in epithelia and also in …
intermediate filament cytoskeleton providing mechanical stability in epithelia and also in …
Desmosomes: regulators of cellular signaling and adhesion in epidermal health and disease
JL Johnson, NA Najor… - Cold Spring …, 2014 - perspectivesinmedicine.cshlp.org
Desmosomes are intercellular junctions that mediate cell–cell adhesion and anchor the
intermediate filament network to the plasma membrane, providing mechanical resilience to …
intermediate filament network to the plasma membrane, providing mechanical resilience to …
Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells
Background The microRNA-200 family participates in the maintenance of an epithelial
phenotype and loss of its expression can result in epithelial to mesenchymal transition …
phenotype and loss of its expression can result in epithelial to mesenchymal transition …
Prognostic value of TP53 gene mutations in myelodysplastic syndromes and acute myeloid leukemia treated with azacitidine
C Bally, L Adès, A Renneville, M Sebert, V Eclache… - Leukemia research, 2014 - Elsevier
TP53 mutations are found in 5–10% of MDS and AML, where they are generally associated
with complex karyotype and an overall poor prognosis. However, the impact of TP53 …
with complex karyotype and an overall poor prognosis. However, the impact of TP53 …
5-Aza-2′-deoxycytidine-mediated reductions in G9A histone methyltransferase and histone H3 K9 di-methylation levels are linked to tumor suppressor gene …
RJ Wozniak, WT Klimecki, SS Lau, Y Feinstein… - Oncogene, 2007 - nature.com
The epigenetic silencing of tumor suppressor genes is a common event during
carcinogenesis, and often involves aberrant DNA methylation and histone modification of …
carcinogenesis, and often involves aberrant DNA methylation and histone modification of …
The isolation of an RNA aptamer targeting to p53 protein with single amino acid mutation
p53, known as a tumor suppressor, is a DNA binding protein that regulates cell cycle,
activates DNA repair proteins, and triggers apoptosis in multicellular animals. More than …
activates DNA repair proteins, and triggers apoptosis in multicellular animals. More than …
miRNA gene promoters are frequent targets of aberrant DNA methylation in human breast cancer
L Vrba, JL Muñoz-Rodríguez, MR Stampfer… - PloS one, 2013 - journals.plos.org
miRNAs are important regulators of gene expression that are frequently deregulated in
cancer, with aberrant DNA methylation being an epigenetic mechanism involved in this …
cancer, with aberrant DNA methylation being an epigenetic mechanism involved in this …
Identification of maspin and S100P as novel hypomethylation targets in pancreatic cancer using global gene expression profiling
N Sato, N Fukushima, H Matsubayashi, M Goggins - Oncogene, 2004 - nature.com
DNA hypomethylation is one of the major epigenetic alterations in human cancers. We have
previously shown that genes identified as hypomethylated in pancreatic cancer are …
previously shown that genes identified as hypomethylated in pancreatic cancer are …
Estradiol-mediated inhibition of DNMT1 decreases p53 expression to induce M2-macrophage polarization in lung cancer progression
YC Chen, MJ Young, HP Chang, CY Liu, CC Lee… - Oncogenesis, 2022 - nature.com
Previous studies indicate that estrogen positively regulates lung cancer progression.
Understanding the reasons will be beneficial for treating women with lung cancer in the …
Understanding the reasons will be beneficial for treating women with lung cancer in the …
Role of maspin in cancer
R Berardi, F Morgese, A Onofri, P Mazzanti… - Clinical and translational …, 2013 - Springer
Maspin (mammary serine protease inhibitor), is a member of the serine protease
inhibitor/non-inhibitor superfamily. Its expression is down-regulated in breast, prostate …
inhibitor/non-inhibitor superfamily. Its expression is down-regulated in breast, prostate …